Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics
The use of modern blood-saving technologies is one of the effective methods of preventing intra-operative bleeding in obstetric practice, however, the effect of local use of terlipressin to reduce blood loss is not sufficiently investigated.The objective: to assess the efficacy of local preventive u...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2020-09-01
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| Series: | Вестник анестезиологии и реаниматологии |
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| Online Access: | https://www.vair-journal.com/jour/article/view/453 |
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| author | Yu. S. Аleksandrovich A. V. Rostovtsev E. S. Kononova K. V. Pshenisnov T. I. Аkimenko |
| author_facet | Yu. S. Аleksandrovich A. V. Rostovtsev E. S. Kononova K. V. Pshenisnov T. I. Аkimenko |
| author_sort | Yu. S. Аleksandrovich |
| collection | DOAJ |
| description | The use of modern blood-saving technologies is one of the effective methods of preventing intra-operative bleeding in obstetric practice, however, the effect of local use of terlipressin to reduce blood loss is not sufficiently investigated.The objective: to assess the efficacy of local preventive use of low doses of terlipressin to reduce of intra-operative blood loss in the cesarean section.Subjects and methods. 105 women who underwent the cesarean section under spinal anesthesia were examined. They were divided into 3 groups depending on the administered dose of terlipressin: Group 1 (n = 35) ‒ 0.2 mg, Group II (n = 35) ‒ 0.4 mg, Group III (n = 35) ‒ control one. The swab-weighing method was used to assess blood loss.Results. In Group I, the blood loss made 6.9% of the total blood volume, in Group II ‒ 7.7%, and in Group III ‒ 13.3%. The frequency of hemotransfusion in Group I was ‒ 0%, in II ‒ 2.9%, in III ‒ 14.3%. No complications and side effects associated with terlipressin use were observed.Conclusion. The use of low doses of terlipressin for prevention purposes has a sufficiently pronounced clinical effect and is not accompanied by any complications. |
| format | Article |
| id | doaj-art-e2cedc983fb240f1b9d84f375d9f1a49 |
| institution | DOAJ |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2020-09-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-e2cedc983fb240f1b9d84f375d9f1a492025-08-20T03:18:55ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532020-09-01174788410.21292/2078-5658-2020-17-4-78-84395Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetricsYu. S. Аleksandrovich0A. V. Rostovtsev1E. S. Kononova2K. V. Pshenisnov3T. I. Аkimenko4St. Petersburg State Pediatric Medical UniversityVoronezh Regional Clinical Hospital no.1Voronezh Regional Clinical Hospital no.1St. Petersburg State Pediatric Medical UniversitySt. Petersburg State Pediatric Medical UniversityThe use of modern blood-saving technologies is one of the effective methods of preventing intra-operative bleeding in obstetric practice, however, the effect of local use of terlipressin to reduce blood loss is not sufficiently investigated.The objective: to assess the efficacy of local preventive use of low doses of terlipressin to reduce of intra-operative blood loss in the cesarean section.Subjects and methods. 105 women who underwent the cesarean section under spinal anesthesia were examined. They were divided into 3 groups depending on the administered dose of terlipressin: Group 1 (n = 35) ‒ 0.2 mg, Group II (n = 35) ‒ 0.4 mg, Group III (n = 35) ‒ control one. The swab-weighing method was used to assess blood loss.Results. In Group I, the blood loss made 6.9% of the total blood volume, in Group II ‒ 7.7%, and in Group III ‒ 13.3%. The frequency of hemotransfusion in Group I was ‒ 0%, in II ‒ 2.9%, in III ‒ 14.3%. No complications and side effects associated with terlipressin use were observed.Conclusion. The use of low doses of terlipressin for prevention purposes has a sufficiently pronounced clinical effect and is not accompanied by any complications.https://www.vair-journal.com/jour/article/view/453cesarean sectionblood lossterlipressinobstetric bleedingprevention |
| spellingShingle | Yu. S. Аleksandrovich A. V. Rostovtsev E. S. Kononova K. V. Pshenisnov T. I. Аkimenko Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics Вестник анестезиологии и реаниматологии cesarean section blood loss terlipressin obstetric bleeding prevention |
| title | Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics |
| title_full | Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics |
| title_fullStr | Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics |
| title_full_unstemmed | Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics |
| title_short | Efficacy of low doses of terlipressin to prevent intra-operative blood loss in obstetrics |
| title_sort | efficacy of low doses of terlipressin to prevent intra operative blood loss in obstetrics |
| topic | cesarean section blood loss terlipressin obstetric bleeding prevention |
| url | https://www.vair-journal.com/jour/article/view/453 |
| work_keys_str_mv | AT yusaleksandrovich efficacyoflowdosesofterlipressintopreventintraoperativebloodlossinobstetrics AT avrostovtsev efficacyoflowdosesofterlipressintopreventintraoperativebloodlossinobstetrics AT eskononova efficacyoflowdosesofterlipressintopreventintraoperativebloodlossinobstetrics AT kvpshenisnov efficacyoflowdosesofterlipressintopreventintraoperativebloodlossinobstetrics AT tiakimenko efficacyoflowdosesofterlipressintopreventintraoperativebloodlossinobstetrics |