In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?

Synthetic analogs of natural nucleotides have long been utilized for structural studies of canonical and noncanonical nucleic acids, including the extensively investigated polymorphic G-quadruplexes (GQs). Dependence on the sequence and nucleotide modifications of the folding landscape of GQs has be...

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Bibliographic Details
Main Author: Janos Sagi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2017/1641845
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