Antigenic analysis of wild-type measles viruses currently isolated in Turkey
The aim of this study was to determine the genetic and antigenic diversity of vaccine-type and wild-type measles viruses by using different antisera in a neutralization assay. Virus strains included genotype A, D3 and D6 clades, and five different groups of antibodies were used. Wild-type mea...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2006-04-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/2608 |
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| _version_ | 1850042883126591488 |
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| author | Gülay Korukluoğlu Pinar Zarakolu |
| author_facet | Gülay Korukluoğlu Pinar Zarakolu |
| author_sort | Gülay Korukluoğlu |
| collection | DOAJ |
| description |
The aim of this study was to determine the genetic and antigenic diversity of vaccine-type and wild-type measles viruses by using different antisera in a neutralization assay. Virus strains included genotype A, D3 and D6 clades, and five different groups of antibodies were used. Wild-type measles viruses isolated in Turkey have been classified as D6 and the others isolated in Japan as D3. Antisera used in the assay were against genotype A, D3 and D6. Regardless of the antigenic diversity, protective antibody level (> or = 1/16) was determined against different genotypes of measles virus.
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| format | Article |
| id | doaj-art-e2c17624283347c781a8628aa2d2bb32 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2006-04-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-e2c17624283347c781a8628aa2d2bb322025-08-20T02:55:24ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212006-04-01482Antigenic analysis of wild-type measles viruses currently isolated in TurkeyGülay Korukluoğlu0Pinar ZarakoluDepartment of Virology, Refik Saydam Hygiene Center, Hacettepe University Faculty of Medicine, Ankara, Turkey. The aim of this study was to determine the genetic and antigenic diversity of vaccine-type and wild-type measles viruses by using different antisera in a neutralization assay. Virus strains included genotype A, D3 and D6 clades, and five different groups of antibodies were used. Wild-type measles viruses isolated in Turkey have been classified as D6 and the others isolated in Japan as D3. Antisera used in the assay were against genotype A, D3 and D6. Regardless of the antigenic diversity, protective antibody level (> or = 1/16) was determined against different genotypes of measles virus. https://turkjpediatr.org/article/view/2608 |
| spellingShingle | Gülay Korukluoğlu Pinar Zarakolu Antigenic analysis of wild-type measles viruses currently isolated in Turkey The Turkish Journal of Pediatrics |
| title | Antigenic analysis of wild-type measles viruses currently isolated in Turkey |
| title_full | Antigenic analysis of wild-type measles viruses currently isolated in Turkey |
| title_fullStr | Antigenic analysis of wild-type measles viruses currently isolated in Turkey |
| title_full_unstemmed | Antigenic analysis of wild-type measles viruses currently isolated in Turkey |
| title_short | Antigenic analysis of wild-type measles viruses currently isolated in Turkey |
| title_sort | antigenic analysis of wild type measles viruses currently isolated in turkey |
| url | https://turkjpediatr.org/article/view/2608 |
| work_keys_str_mv | AT gulaykorukluoglu antigenicanalysisofwildtypemeaslesvirusescurrentlyisolatedinturkey AT pinarzarakolu antigenicanalysisofwildtypemeaslesvirusescurrentlyisolatedinturkey |