Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress

BackgroundRecurrent abdominal pain (RAP) is one of the most common gastrointestinal disorders in children. The aim of this study was to investigate the relationship between RAP and Helicobacter pylori infection in children in Wuhu, China as well as the risk factors for Helicobacter pylori infection...

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Main Authors: Xiaohui Bai, Huiru Cao, Liuming Zhu, Xiaomin Wu, Guixiang Wang, Wenchao Yu, Yong Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2024.1481125/full
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author Xiaohui Bai
Huiru Cao
Liuming Zhu
Xiaomin Wu
Guixiang Wang
Wenchao Yu
Yong Gu
author_facet Xiaohui Bai
Huiru Cao
Liuming Zhu
Xiaomin Wu
Guixiang Wang
Wenchao Yu
Yong Gu
author_sort Xiaohui Bai
collection DOAJ
description BackgroundRecurrent abdominal pain (RAP) is one of the most common gastrointestinal disorders in children. The aim of this study was to investigate the relationship between RAP and Helicobacter pylori infection in children in Wuhu, China as well as the risk factors for Helicobacter pylori infection in this region.Materials and methodsIn this cross-sectional survey, we randomly selected children aged 6–17 years who underwent health examinations at three public hospital examination centers in Wuhu city, Anhui Province, China. Helicobacter pylori infection was assessed by a 13C-urea breath test (UBT) kit. Questionnaires were custom designed to obtain data on behavioral, sociodemographic, and environmental characteristics, and to investigate the relationship between RAP and Helicobacter pylori infection in children.ResultsA total of 1,187 children aged 6–17 years were enrolled, among these children, 182 were diagnosed with RAP, with an incidence rate of 15.3%. A total of 266 children were infected with Helicobacter pylori, with an infection rate of 22.4%. Multivariate regression analysis revealed that physical activity for &lt;1 h/day and academic stress are associated with RAP in children, whereas Helicobacter pylori infection, age, sex, body mass index (BMI), and fast-food consumption are not associated with RAP in children. Our research also found that the risk of Helicobacter pylori infection increases with age in children. Risk factors for Helicobacter pylori infection in children include left-behind children, poor hygiene habits, family history of Helicobacter pylori infection, and mother with low cultural levels.ConclusionsRecurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but strongly associated with &lt;1 h/day physical activity and academic stress.
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spelling doaj-art-e2b0c9349757496d8dfa6ef9f597cb2a2025-08-20T02:19:21ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602024-12-011210.3389/fped.2024.14811251481125Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stressXiaohui Bai0Huiru Cao1Liuming Zhu2Xiaomin Wu3Guixiang Wang4Wenchao Yu5Yong Gu6Department of Pediatrics, Graduate School, Wannan Medical College, Wuhu, Anhui, ChinaLaboratory of Digestion, Department of Gastroenterology, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, ChinaLaboratory of Digestion, Department of Gastroenterology, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, ChinaDepartment of Pediatrics, Wuhu No.1 Peoples’ Hospital, Wuhu, Anhui, ChinaDepartment of Gastroenterology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, ChinaDepartment of Pediatrics, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, ChinaDepartment of Pediatrics, Yijishan Hospital, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, ChinaBackgroundRecurrent abdominal pain (RAP) is one of the most common gastrointestinal disorders in children. The aim of this study was to investigate the relationship between RAP and Helicobacter pylori infection in children in Wuhu, China as well as the risk factors for Helicobacter pylori infection in this region.Materials and methodsIn this cross-sectional survey, we randomly selected children aged 6–17 years who underwent health examinations at three public hospital examination centers in Wuhu city, Anhui Province, China. Helicobacter pylori infection was assessed by a 13C-urea breath test (UBT) kit. Questionnaires were custom designed to obtain data on behavioral, sociodemographic, and environmental characteristics, and to investigate the relationship between RAP and Helicobacter pylori infection in children.ResultsA total of 1,187 children aged 6–17 years were enrolled, among these children, 182 were diagnosed with RAP, with an incidence rate of 15.3%. A total of 266 children were infected with Helicobacter pylori, with an infection rate of 22.4%. Multivariate regression analysis revealed that physical activity for &lt;1 h/day and academic stress are associated with RAP in children, whereas Helicobacter pylori infection, age, sex, body mass index (BMI), and fast-food consumption are not associated with RAP in children. Our research also found that the risk of Helicobacter pylori infection increases with age in children. Risk factors for Helicobacter pylori infection in children include left-behind children, poor hygiene habits, family history of Helicobacter pylori infection, and mother with low cultural levels.ConclusionsRecurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but strongly associated with &lt;1 h/day physical activity and academic stress.https://www.frontiersin.org/articles/10.3389/fped.2024.1481125/fullchildrenrecurrent abdominal painHelicobacter pylori infectionphysical activityacademic stress
spellingShingle Xiaohui Bai
Huiru Cao
Liuming Zhu
Xiaomin Wu
Guixiang Wang
Wenchao Yu
Yong Gu
Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
Frontiers in Pediatrics
children
recurrent abdominal pain
Helicobacter pylori infection
physical activity
academic stress
title Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
title_full Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
title_fullStr Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
title_full_unstemmed Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
title_short Recurrent abdominal pain in children in Wuhu, China was not associated with Helicobacter pylori infection, but associated with <1 h/day physical activity and academic stress
title_sort recurrent abdominal pain in children in wuhu china was not associated with helicobacter pylori infection but associated with 1 h day physical activity and academic stress
topic children
recurrent abdominal pain
Helicobacter pylori infection
physical activity
academic stress
url https://www.frontiersin.org/articles/10.3389/fped.2024.1481125/full
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