Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer
Acute liver failure (ALF) is a rare presentation of liver metastases. Although cases of ALF from metastatic disease have been reported, etiologies have been largely confined to lymphoma, metastatic breast, lung, and gastric cancers. ALF from medullary thyroid cancer (MTC) has never been reported. We...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2011/603757 |
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| author | Emmanuel C. Gorospe Jemilat Badamas |
| author_facet | Emmanuel C. Gorospe Jemilat Badamas |
| author_sort | Emmanuel C. Gorospe |
| collection | DOAJ |
| description | Acute liver failure (ALF) is a rare presentation of liver metastases. Although cases of ALF from metastatic disease have been reported, etiologies have been largely confined to lymphoma, metastatic breast, lung, and gastric cancers. ALF from medullary thyroid cancer (MTC) has never been reported. We present a 59-year-old male with newly diagnosed MTC, who was admitted with ALF. He presented with jaundice, hepatic encephalopathy, and synthetic dysfunction. His clinical course was marked by rapid decompensation within 6 days from initial presentation of jaundice to development of hepatic coma. Although liver metastases from medullary thyroid cancer have been reported, to our knowledge, this is the first described case of MTC resulting in acute liver failure. |
| format | Article |
| id | doaj-art-e2a8809c6d264c3e8e2b83870e4d712f |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-e2a8809c6d264c3e8e2b83870e4d712f2025-02-03T01:24:33ZengWileyCase Reports in Hepatology2090-65872090-65952011-01-01201110.1155/2011/603757603757Acute Liver Failure Secondary to Metastatic Medullary Thyroid CancerEmmanuel C. Gorospe0Jemilat Badamas1Saint Marys Hospital, Mayo Clinic, 1216 Second Street SW, Rochester, MN 55902, USASaint Marys Hospital, Mayo Clinic, 1216 Second Street SW, Rochester, MN 55902, USAAcute liver failure (ALF) is a rare presentation of liver metastases. Although cases of ALF from metastatic disease have been reported, etiologies have been largely confined to lymphoma, metastatic breast, lung, and gastric cancers. ALF from medullary thyroid cancer (MTC) has never been reported. We present a 59-year-old male with newly diagnosed MTC, who was admitted with ALF. He presented with jaundice, hepatic encephalopathy, and synthetic dysfunction. His clinical course was marked by rapid decompensation within 6 days from initial presentation of jaundice to development of hepatic coma. Although liver metastases from medullary thyroid cancer have been reported, to our knowledge, this is the first described case of MTC resulting in acute liver failure.http://dx.doi.org/10.1155/2011/603757 |
| spellingShingle | Emmanuel C. Gorospe Jemilat Badamas Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer Case Reports in Hepatology |
| title | Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer |
| title_full | Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer |
| title_fullStr | Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer |
| title_full_unstemmed | Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer |
| title_short | Acute Liver Failure Secondary to Metastatic Medullary Thyroid Cancer |
| title_sort | acute liver failure secondary to metastatic medullary thyroid cancer |
| url | http://dx.doi.org/10.1155/2011/603757 |
| work_keys_str_mv | AT emmanuelcgorospe acuteliverfailuresecondarytometastaticmedullarythyroidcancer AT jemilatbadamas acuteliverfailuresecondarytometastaticmedullarythyroidcancer |