Associations of serum Klotho with diabetic kidney disease prevalence and mortality: insights from a nationally representative U.S. cohort

Associations of serum Klotho with diabetic kidney disease prevalence and mortality: insights from a nationally representative U.S. cohort

Abstract Background Serum Klotho, a biomarker associated with anti-aging, has been implicated in kidney disease. However, there is a lack of robust evidence for the relationship between the serum Klotho and diabetic kidney disease (DKD). This study aimed to investigate the association of the serum K...

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Main Authors: Peichen Xie, Dingding Wang, Meng Zhang, Lanping Jiang, Yagui Qiu, Yiqin Wang, Siyang Ye, Manhuai Zhang, Li Tan, Sixiu Chen, Qianling Liu, Huajing Peng, Suchun Li, Jianbo Li, Qiong Wen, Leigang Jin, Xiaoping Wu, Kam Wa Chan, Sydney C. W. Tang, Wei Chen, Bin Li
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Klotho
Diabetic kidney disease
Prevalence
Mortality
NHANES
Online Access:https://doi.org/10.1186/s13098-025-01729-1
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