Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis

Background. Clinical presentations of acute appendicitis (AA) and acute right-sided colonic diverticulitis (ARCD) are similar. However, the usual treatment for each disease differs between surgical and conservative management. The aim of this study was to identify clinical differences between AA and...

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Main Authors: Ji Ho Song, Yong Won Kim, Sanghun Lee, Han Ho Do, Jun Seok Seo, Jeong Hun Lee, Seung Chul Lee
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2020/4947192
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author Ji Ho Song
Yong Won Kim
Sanghun Lee
Han Ho Do
Jun Seok Seo
Jeong Hun Lee
Seung Chul Lee
author_facet Ji Ho Song
Yong Won Kim
Sanghun Lee
Han Ho Do
Jun Seok Seo
Jeong Hun Lee
Seung Chul Lee
author_sort Ji Ho Song
collection DOAJ
description Background. Clinical presentations of acute appendicitis (AA) and acute right-sided colonic diverticulitis (ARCD) are similar. However, the usual treatment for each disease differs between surgical and conservative management. The aim of this study was to identify clinical differences between AA and ARCD. Method. We performed a single-center retrospective study on adult patients, with uncomplicated AA and ARCD confirmed by computed tomography, who visited an emergency department between March 2018 and August 2019. Clinical variables including past medical history, presented symptoms and signs, and laboratory findings were compared between the two groups. A logistic regression analysis was subsequently performed to differentiate ARCD from AA based on results of univariate analyses. Results. A total of 212 (79.1%) and 56 (20.9%) patients were enrolled in AA and ARSD groups, respectively. Logistic regression analysis revealed that a past history of diverticulitis [OR: 102.679 (95% CI: 9.964–1058.055), p<0.001] was associated with ARCD, while ketonuria [OR: 2.907 (95% CI: 1.091–7.745), p=0.033], anorexia [OR: 21.544 (95% CI: 3.905–118.868), p<0.001], and neutrophilia [OR: 3.406 (95% CI: 1.243–9.336), p=0.017] were associated with AA. Conclusion. Anorexia, neutrophilia, and ketonuria were predictors of AA while a history of diverticulitis was a predictor of ARCD.
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spelling doaj-art-e29ef29b41f444439140af247ad46f652025-08-20T03:21:06ZengWileyEmergency Medicine International2090-28402090-28592020-01-01202010.1155/2020/49471924947192Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic DiverticulitisJi Ho Song0Yong Won Kim1Sanghun Lee2Han Ho Do3Jun Seok Seo4Jeong Hun Lee5Seung Chul Lee6Department of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaDepartment of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaDepartment of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaDepartment of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaDepartment of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaDepartment of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaDepartment of Emergency Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Republic of KoreaBackground. Clinical presentations of acute appendicitis (AA) and acute right-sided colonic diverticulitis (ARCD) are similar. However, the usual treatment for each disease differs between surgical and conservative management. The aim of this study was to identify clinical differences between AA and ARCD. Method. We performed a single-center retrospective study on adult patients, with uncomplicated AA and ARCD confirmed by computed tomography, who visited an emergency department between March 2018 and August 2019. Clinical variables including past medical history, presented symptoms and signs, and laboratory findings were compared between the two groups. A logistic regression analysis was subsequently performed to differentiate ARCD from AA based on results of univariate analyses. Results. A total of 212 (79.1%) and 56 (20.9%) patients were enrolled in AA and ARSD groups, respectively. Logistic regression analysis revealed that a past history of diverticulitis [OR: 102.679 (95% CI: 9.964–1058.055), p<0.001] was associated with ARCD, while ketonuria [OR: 2.907 (95% CI: 1.091–7.745), p=0.033], anorexia [OR: 21.544 (95% CI: 3.905–118.868), p<0.001], and neutrophilia [OR: 3.406 (95% CI: 1.243–9.336), p=0.017] were associated with AA. Conclusion. Anorexia, neutrophilia, and ketonuria were predictors of AA while a history of diverticulitis was a predictor of ARCD.http://dx.doi.org/10.1155/2020/4947192
spellingShingle Ji Ho Song
Yong Won Kim
Sanghun Lee
Han Ho Do
Jun Seok Seo
Jeong Hun Lee
Seung Chul Lee
Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis
Emergency Medicine International
title Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis
title_full Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis
title_fullStr Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis
title_full_unstemmed Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis
title_short Clinical Difference between Acute Appendicitis and Acute Right-Sided Colonic Diverticulitis
title_sort clinical difference between acute appendicitis and acute right sided colonic diverticulitis
url http://dx.doi.org/10.1155/2020/4947192
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