Early Fungicidal Activity as a Candidate Surrogate Endpoint for All-Cause Mortality in Cryptococcal Meningitis: A Systematic Review of the Evidence.
<h4>Background</h4>Cryptococcal meningitis (CM) is a leading cause of HIV-associated mortality. In clinical trials evaluating treatments for CM, biomarkers of early fungicidal activity (EFA) in cerebrospinal fluid (CSF) have been proposed as candidate surrogate endpoints for all- cause m...
Saved in:
| Main Authors: | Jairo M Montezuma-Rusca, John H Powers, Dean Follmann, Jing Wang, Brigit Sullivan, Peter R Williamson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0159727&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Batf3-cDC1 control Th1 and fungicidal responses during cryptococcal meningitis: is this enough to control meningitis?
by: Carolina Coelho
Published: (2024-10-01) -
Alcohol production in cryptococcal meningitis
by: Viroj Wiwanitkit
Published: (2012-03-01) -
Fatal cryptococcal meningitis in an immunocompetent patient
by: Minoosh Shabani, et al.
Published: (2025-06-01) -
Cutaneous lesions as marker of cryptococcal meningitis
by: J L Som, et al.
Published: (2015-01-01) -
Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis.
by: Anil A Panackal, et al.
Published: (2015-05-01)