Activation of C-fiber nociceptors by low-power diode laser

ABSTRACT Objective The evaluation of selective activation of C-fibers to record evoked potentials using the association of low-power diode laser (810 nm), tiny-area stimulation and skin-blackening. Method Laser-evoked potentials (LEPs) were obtained from 20 healthy young subjects. An aluminum pl...

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Main Authors: Eduardo Azevedo, Andressa Silva, Raquel Martins, Monica L. Andersen, Sergio Tufik, Gilberto M. Manzano
Format: Article
Language:English
Published: Thieme Revinter Publicações 2016-03-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000300009&lng=en&tlng=en
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author Eduardo Azevedo
Andressa Silva
Raquel Martins
Monica L. Andersen
Sergio Tufik
Gilberto M. Manzano
author_facet Eduardo Azevedo
Andressa Silva
Raquel Martins
Monica L. Andersen
Sergio Tufik
Gilberto M. Manzano
author_sort Eduardo Azevedo
collection DOAJ
description ABSTRACT Objective The evaluation of selective activation of C-fibers to record evoked potentials using the association of low-power diode laser (810 nm), tiny-area stimulation and skin-blackening. Method Laser-evoked potentials (LEPs) were obtained from 20 healthy young subjects. An aluminum plate with one thin hole was attached to the laser probe to provide tiny-area stimulation of the hand dorsum and the stimulated area was covered with black ink. Results The mean intensity used for eliciting the ultra-late laser-evoked potential (ULEP) was 70 ± 32 mW. All subjects showed a clear biphasic potential that comprised a negative peak (806 ± 61 ms) and a positive deflection (1033 ± 60 ms), corresponding to the ULEP related to C-fiber activation. Conclusion C-fiber-evoked responses can be obtained using a very low-power diode laser when stimulation is applied to tiny areas of darkened skin. This strategy offers a non-invasive and easy methodology that minimizes damage to the tissue.
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issn 1678-4227
language English
publishDate 2016-03-01
publisher Thieme Revinter Publicações
record_format Article
series Arquivos de Neuro-Psiquiatria
spelling doaj-art-e293fd00f54b4231a5f3457ce99063052025-08-20T03:21:06ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272016-03-0174322322710.1590/0004-282X20160018S0004-282X2016000300009Activation of C-fiber nociceptors by low-power diode laserEduardo AzevedoAndressa SilvaRaquel MartinsMonica L. AndersenSergio TufikGilberto M. ManzanoABSTRACT Objective The evaluation of selective activation of C-fibers to record evoked potentials using the association of low-power diode laser (810 nm), tiny-area stimulation and skin-blackening. Method Laser-evoked potentials (LEPs) were obtained from 20 healthy young subjects. An aluminum plate with one thin hole was attached to the laser probe to provide tiny-area stimulation of the hand dorsum and the stimulated area was covered with black ink. Results The mean intensity used for eliciting the ultra-late laser-evoked potential (ULEP) was 70 ± 32 mW. All subjects showed a clear biphasic potential that comprised a negative peak (806 ± 61 ms) and a positive deflection (1033 ± 60 ms), corresponding to the ULEP related to C-fiber activation. Conclusion C-fiber-evoked responses can be obtained using a very low-power diode laser when stimulation is applied to tiny areas of darkened skin. This strategy offers a non-invasive and easy methodology that minimizes damage to the tissue.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000300009&lng=en&tlng=enpotenciais evocados a laserfibras Cnocicepçãopercepção dolorosa
spellingShingle Eduardo Azevedo
Andressa Silva
Raquel Martins
Monica L. Andersen
Sergio Tufik
Gilberto M. Manzano
Activation of C-fiber nociceptors by low-power diode laser
Arquivos de Neuro-Psiquiatria
potenciais evocados a laser
fibras C
nocicepção
percepção dolorosa
title Activation of C-fiber nociceptors by low-power diode laser
title_full Activation of C-fiber nociceptors by low-power diode laser
title_fullStr Activation of C-fiber nociceptors by low-power diode laser
title_full_unstemmed Activation of C-fiber nociceptors by low-power diode laser
title_short Activation of C-fiber nociceptors by low-power diode laser
title_sort activation of c fiber nociceptors by low power diode laser
topic potenciais evocados a laser
fibras C
nocicepção
percepção dolorosa
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2016000300009&lng=en&tlng=en
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AT monicalandersen activationofcfibernociceptorsbylowpowerdiodelaser
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