Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction.

Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction.

Osteopontin (SPP1) is an important bone matrix mediator found to have key roles in inflammation and immunity. SPP1 genetic polymorphisms and increased osteopontin protein levels have been reported to be associated with SLE in small patient collections. The present study evaluates association between...

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Main Authors: Shizhong Han, Joel M Guthridge, Isaac T W Harley, Andrea L Sestak, Xana Kim-Howard, Kenneth M Kaufman, Bahram Namjou, Harshal Deshmukh, Gail Bruner, Luis R Espinoza, Gary S Gilkeson, John B Harley, Judith A James, Swapan K Nath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001757&type=printable
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