Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance
The study demonstrated possible design of a medicinal formulation in the form of suppositories comprising human recombinant interferon-α2 and dry aloe extract. The approaches to the development of the suppositories were technology - derived. No interaction between the active and auxiliary components...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Publishing House OKI"
2020-05-01
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| Series: | Антибиотики и Химиотерапия |
| Subjects: | |
| Online Access: | https://www.antibiotics-chemotherapy.ru/jour/article/view/416 |
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| _version_ | 1849389233647648768 |
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| author | R. A. Abramovich V. A. Bykov I. A. Elagina N. A. Papazona A. N. Vorobyev |
| author_facet | R. A. Abramovich V. A. Bykov I. A. Elagina N. A. Papazona A. N. Vorobyev |
| author_sort | R. A. Abramovich |
| collection | DOAJ |
| description | The study demonstrated possible design of a medicinal formulation in the form of suppositories comprising human recombinant interferon-α2 and dry aloe extract. The approaches to the development of the suppositories were technology - derived. No interaction between the active and auxiliary components was proved by solid state1H-NMR spectroscopy. The specific activity of the drug was investigated. |
| format | Article |
| id | doaj-art-e290957dd5934a4f967e697929dd09aa |
| institution | Kabale University |
| issn | 0235-2990 |
| language | Russian |
| publishDate | 2020-05-01 |
| publisher | LLC "Publishing House OKI" |
| record_format | Article |
| series | Антибиотики и Химиотерапия |
| spelling | doaj-art-e290957dd5934a4f967e697929dd09aa2025-08-20T03:42:01ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01571-21316415Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological SubstanceR. A. Abramovich0V. A. Bykov1I. A. Elagina2N. A. Papazona3A. N. Vorobyev4Russian University of People's FriendshipRussian University of People's FriendshipRussian University of People's FriendshipRussian University of People's FriendshipRussian University of People's FriendshipThe study demonstrated possible design of a medicinal formulation in the form of suppositories comprising human recombinant interferon-α2 and dry aloe extract. The approaches to the development of the suppositories were technology - derived. No interaction between the active and auxiliary components was proved by solid state1H-NMR spectroscopy. The specific activity of the drug was investigated.https://www.antibiotics-chemotherapy.ru/jour/article/view/416human recombinant interferon- α2aloe extractsuppositories<sup>1</sup>h-nmr spectroscopy |
| spellingShingle | R. A. Abramovich V. A. Bykov I. A. Elagina N. A. Papazona A. N. Vorobyev Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance Антибиотики и Химиотерапия human recombinant interferon- α2 aloe extract suppositories <sup>1</sup>h-nmr spectroscopy |
| title | Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance |
| title_full | Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance |
| title_fullStr | Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance |
| title_full_unstemmed | Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance |
| title_short | Scientific Approaches to Development of Medicinal Formulation Based on Biotechnological Substance |
| title_sort | scientific approaches to development of medicinal formulation based on biotechnological substance |
| topic | human recombinant interferon- α2 aloe extract suppositories <sup>1</sup>h-nmr spectroscopy |
| url | https://www.antibiotics-chemotherapy.ru/jour/article/view/416 |
| work_keys_str_mv | AT raabramovich scientificapproachestodevelopmentofmedicinalformulationbasedonbiotechnologicalsubstance AT vabykov scientificapproachestodevelopmentofmedicinalformulationbasedonbiotechnologicalsubstance AT iaelagina scientificapproachestodevelopmentofmedicinalformulationbasedonbiotechnologicalsubstance AT napapazona scientificapproachestodevelopmentofmedicinalformulationbasedonbiotechnologicalsubstance AT anvorobyev scientificapproachestodevelopmentofmedicinalformulationbasedonbiotechnologicalsubstance |