Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the m...

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Main Authors: Philip Wells, Andrea De Giacomo, Lucia Margari, Maria Giuseppina Petruzzelli, Fiona McNicholas, Helen Keeley, Mario Speranza, Giuseppe Carrà, Jason Madan, James McDonald, Jatinder Singh, Federico Fiori, Leanne Walker, Helena Tuomainen, Sarah Miller, Laura Adams, Mathilde Mastroianni, Natalie Heaney, Kate Lievesley, Ilyas Sagar-Ouriaghli, Giovanni Allibrio, Rebecca Appleton, Nikolina Davidović, Giovanni de Girolamo, Katarina Dodig-Ćurković, Tomislav Franić, Charlotte Gatherer, Elisa Gheza, Lidia Manenti, Athanasios Maras, Francesco Margari, Adriana Pastore, Moli Paul, Diane Purper-Ouakil, Francesco Rinaldi, Vehbi Sakar, Giulia Signorini, Cathy Street, Priya Tah, Sabine Tremmery, Amanda Tuffrey, Anna Wilson, Erika Riva, Renata Nacinovich, Alastair Canaway, Claire Daffern, Marina Danckaerts, Frederique Bonnet-Brilhault, Frank C Verhulst, Emiliano Monzani, Paola Martinelli, Swaran P Singh, Ottaviano Martinelli, Gwen C Dieleman, James Griffin, Sonja Aslan, Frédérick Russet, James Kirwan, Ashley Liew, Véronique Humbertclaude, Paramala J Santosh, Maria Migone, Suzanne E Gerritsen, Larissa S van Bodegom, Mathilde M Overbeek, Angelo Bertani, Maria G Cataldo, Patrizia Conti, David Da Fonseca, Cecilia Ferrari, Gaëlle Hendrickx, Alfred Kolozsvari, Flavia Micol Levi, Virginie Maurice, Lesley O'Hara, Veronique de Roeck, Melanie C Saam, Anne Sartor, Aurélie Schandrin, Ulrike M E Schulze, Elena Tanase, Therese A M J van Amelsvoort, Marco Armando, Nadia Baccanelli, Monica Balaudo, Fabia Bergamo, Jo Berriman, Chrystèle Bodier Rethore, Albert Boon, Karen Braamse, Ulrike Breuninger, Maura Buttiglione, Sarah Buttle, Marco Cammarano, Fortunata Cantini, Cristiano Cappellari, Marta Carenini, Isabelle Charvin, Krizia Chianura, Philippa Coleman, Annalisa Colonna, Patrizia Conese, Raffaella Costanzo, Peter Dineen, Jean-Pierre Ermans, Alan Farmer, Jörg M Fegert, Alessandro Ferrari, Sabrina Ferrari, Giuliana Galea, Michela Gatta, Giacomo Goglia, MariaRosa Grandetto, Elaine Healy, Keith Holmes, Nicola Ingravallo, Roberta Invernizzi, Renaud Jardri, Caoimhe Kelly, Meghan Killilea, Catherine Klockaerts, Vlatka Kovač, Hélène Lida-Pulik, Christel Lippens, Fionnuala Lynch, Francesca Macchi, Leighton McFadden, Deny Menghini, Giorgia Morini, Todor Mutafov, Cristina Negrinotti, Emmanuel Nelis, Francesca Neri, Paulina Nikolova, Marzia Nossa, Michele Noterdaeme, Francesca Operto, Vittoria Panaro, Aesa Parenti, Vinuthna Pemmaraju, Ann Pepermans, Anna Presicci, Catherine Prigent, Laura Rivolta, Anne Roekens, Ben Rogers, Pablo Ronzini, Selena Salvetti, Tanveer Sandhu, Renate Schepker, Paolo Scocco, Marco Siviero, Michael Slowik, Courtney Smyth, Maria Antonietta Spadone, Paolo Stagi, Pamela Stagni, Fabrizio Starace, Patrizia Stoppa, Lucia Tansini, Cecilia Toselli, Guido Trabucchi, Maria Tubito, Arno van Dam, Hanne Van Gutschoven, Dirk van West, Fabio Vanni, Chiara Vannicola, Cristiana Varuzza, Pamela Varvara, Patrizia Ventura, Stefano Vicari, Stefania Vicini, Carolin von Bentzel, Beata Williams, Marina Zabarella, Anna Zamboni, Edda Zanetti
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Published: BMJ Publishing Group 2021-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/12/e053373.full
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author Philip Wells
Andrea De Giacomo
Lucia Margari
Maria Giuseppina Petruzzelli
Fiona McNicholas
Helen Keeley
Mario Speranza
Giuseppe Carrà
Jason Madan
James McDonald
Jatinder Singh
Federico Fiori
Leanne Walker
Helena Tuomainen
Sarah Miller
Laura Adams
Mathilde Mastroianni
Natalie Heaney
Kate Lievesley
Ilyas Sagar-Ouriaghli
Giovanni Allibrio
Rebecca Appleton
Nikolina Davidović
Giovanni de Girolamo
Katarina Dodig-Ćurković
Tomislav Franić
Charlotte Gatherer
Elisa Gheza
Lidia Manenti
Athanasios Maras
Francesco Margari
Adriana Pastore
Moli Paul
Diane Purper-Ouakil
Francesco Rinaldi
Vehbi Sakar
Giulia Signorini
Cathy Street
Priya Tah
Sabine Tremmery
Amanda Tuffrey
Anna Wilson
Erika Riva
Renata Nacinovich
Alastair Canaway
Claire Daffern
Marina Danckaerts
Frederique Bonnet-Brilhault
Frank C Verhulst
Emiliano Monzani
Paola Martinelli
Swaran P Singh
Ottaviano Martinelli
Gwen C Dieleman
James Griffin
Sonja Aslan
Frédérick Russet
James Kirwan
Ashley Liew
Véronique Humbertclaude
Paramala J Santosh
Maria Migone
Suzanne E Gerritsen
Larissa S van Bodegom
Mathilde M Overbeek
Angelo Bertani
Maria G Cataldo
Patrizia Conti
David Da Fonseca
Cecilia Ferrari
Gaëlle Hendrickx
Alfred Kolozsvari
Flavia Micol Levi
Virginie Maurice
Lesley O'Hara
Veronique de Roeck
Melanie C Saam
Anne Sartor
Aurélie Schandrin
Ulrike M E Schulze
Elena Tanase
Therese A M J van Amelsvoort
Marco Armando
Nadia Baccanelli
Monica Balaudo
Fabia Bergamo
Jo Berriman
Chrystèle Bodier Rethore
Albert Boon
Karen Braamse
Ulrike Breuninger
Maura Buttiglione
Sarah Buttle
Marco Cammarano
Fortunata Cantini
Cristiano Cappellari
Marta Carenini
Isabelle Charvin
Krizia Chianura
Philippa Coleman
Annalisa Colonna
Patrizia Conese
Raffaella Costanzo
Peter Dineen
Jean-Pierre Ermans
Alan Farmer
Jörg M Fegert
Alessandro Ferrari
Sabrina Ferrari
Giuliana Galea
Michela Gatta
Giacomo Goglia
MariaRosa Grandetto
Elaine Healy
Keith Holmes
Nicola Ingravallo
Roberta Invernizzi
Renaud Jardri
Caoimhe Kelly
Meghan Killilea
Catherine Klockaerts
Vlatka Kovač
Hélène Lida-Pulik
Christel Lippens
Fionnuala Lynch
Francesca Macchi
Leighton McFadden
Deny Menghini
Giorgia Morini
Todor Mutafov
Cristina Negrinotti
Emmanuel Nelis
Francesca Neri
Paulina Nikolova
Marzia Nossa
Michele Noterdaeme
Francesca Operto
Vittoria Panaro
Aesa Parenti
Vinuthna Pemmaraju
Ann Pepermans
Anna Presicci
Catherine Prigent
Laura Rivolta
Anne Roekens
Ben Rogers
Pablo Ronzini
Selena Salvetti
Tanveer Sandhu
Renate Schepker
Paolo Scocco
Marco Siviero
Michael Slowik
Courtney Smyth
Maria Antonietta Spadone
Paolo Stagi
Pamela Stagni
Fabrizio Starace
Patrizia Stoppa
Lucia Tansini
Cecilia Toselli
Guido Trabucchi
Maria Tubito
Arno van Dam
Hanne Van Gutschoven
Dirk van West
Fabio Vanni
Chiara Vannicola
Cristiana Varuzza
Pamela Varvara
Patrizia Ventura
Stefano Vicari
Stefania Vicini
Carolin von Bentzel
Beata Williams
Marina Zabarella
Anna Zamboni
Edda Zanetti
author_facet Philip Wells
Andrea De Giacomo
Lucia Margari
Maria Giuseppina Petruzzelli
Fiona McNicholas
Helen Keeley
Mario Speranza
Giuseppe Carrà
Jason Madan
James McDonald
Jatinder Singh
Federico Fiori
Leanne Walker
Helena Tuomainen
Sarah Miller
Laura Adams
Mathilde Mastroianni
Natalie Heaney
Kate Lievesley
Ilyas Sagar-Ouriaghli
Giovanni Allibrio
Rebecca Appleton
Nikolina Davidović
Giovanni de Girolamo
Katarina Dodig-Ćurković
Tomislav Franić
Charlotte Gatherer
Elisa Gheza
Lidia Manenti
Athanasios Maras
Francesco Margari
Adriana Pastore
Moli Paul
Diane Purper-Ouakil
Francesco Rinaldi
Vehbi Sakar
Giulia Signorini
Cathy Street
Priya Tah
Sabine Tremmery
Amanda Tuffrey
Anna Wilson
Erika Riva
Renata Nacinovich
Alastair Canaway
Claire Daffern
Marina Danckaerts
Frederique Bonnet-Brilhault
Frank C Verhulst
Emiliano Monzani
Paola Martinelli
Swaran P Singh
Ottaviano Martinelli
Gwen C Dieleman
James Griffin
Sonja Aslan
Frédérick Russet
James Kirwan
Ashley Liew
Véronique Humbertclaude
Paramala J Santosh
Maria Migone
Suzanne E Gerritsen
Larissa S van Bodegom
Mathilde M Overbeek
Angelo Bertani
Maria G Cataldo
Patrizia Conti
David Da Fonseca
Cecilia Ferrari
Gaëlle Hendrickx
Alfred Kolozsvari
Flavia Micol Levi
Virginie Maurice
Lesley O'Hara
Veronique de Roeck
Melanie C Saam
Anne Sartor
Aurélie Schandrin
Ulrike M E Schulze
Elena Tanase
Therese A M J van Amelsvoort
Marco Armando
Nadia Baccanelli
Monica Balaudo
Fabia Bergamo
Jo Berriman
Chrystèle Bodier Rethore
Albert Boon
Karen Braamse
Ulrike Breuninger
Maura Buttiglione
Sarah Buttle
Marco Cammarano
Fortunata Cantini
Cristiano Cappellari
Marta Carenini
Isabelle Charvin
Krizia Chianura
Philippa Coleman
Annalisa Colonna
Patrizia Conese
Raffaella Costanzo
Peter Dineen
Jean-Pierre Ermans
Alan Farmer
Jörg M Fegert
Alessandro Ferrari
Sabrina Ferrari
Giuliana Galea
Michela Gatta
Giacomo Goglia
MariaRosa Grandetto
Elaine Healy
Keith Holmes
Nicola Ingravallo
Roberta Invernizzi
Renaud Jardri
Caoimhe Kelly
Meghan Killilea
Catherine Klockaerts
Vlatka Kovač
Hélène Lida-Pulik
Christel Lippens
Fionnuala Lynch
Francesca Macchi
Leighton McFadden
Deny Menghini
Giorgia Morini
Todor Mutafov
Cristina Negrinotti
Emmanuel Nelis
Francesca Neri
Paulina Nikolova
Marzia Nossa
Michele Noterdaeme
Francesca Operto
Vittoria Panaro
Aesa Parenti
Vinuthna Pemmaraju
Ann Pepermans
Anna Presicci
Catherine Prigent
Laura Rivolta
Anne Roekens
Ben Rogers
Pablo Ronzini
Selena Salvetti
Tanveer Sandhu
Renate Schepker
Paolo Scocco
Marco Siviero
Michael Slowik
Courtney Smyth
Maria Antonietta Spadone
Paolo Stagi
Pamela Stagni
Fabrizio Starace
Patrizia Stoppa
Lucia Tansini
Cecilia Toselli
Guido Trabucchi
Maria Tubito
Arno van Dam
Hanne Van Gutschoven
Dirk van West
Fabio Vanni
Chiara Vannicola
Cristiana Varuzza
Pamela Varvara
Patrizia Ventura
Stefano Vicari
Stefania Vicini
Carolin von Bentzel
Beata Williams
Marina Zabarella
Anna Zamboni
Edda Zanetti
author_sort Philip Wells
collection DOAJ
description Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports.Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at.Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be ‘markedly ill’, ‘severely ill’ or ‘among the most extremely ill’ by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year.Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared.Trial registration number NCT03013595.
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spelling doaj-art-e28bba3efa0e4a4b887f5ccceb688ef02025-08-20T01:59:13ZengBMJ Publishing GroupBMJ Open2044-60552021-12-01111210.1136/bmjopen-2021-053373Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in EuropePhilip WellsAndrea De GiacomoLucia MargariMaria Giuseppina PetruzzelliFiona McNicholas0Helen KeeleyMario SperanzaGiuseppe CarràJason Madan1James McDonald2Jatinder Singh3Federico Fiori4Leanne Walker5Helena Tuomainen6Sarah MillerLaura AdamsMathilde Mastroianni7Natalie Heaney8Kate Lievesley9Ilyas Sagar-Ouriaghli10Giovanni AllibrioRebecca Appleton11Nikolina Davidović12Giovanni de Girolamo13Katarina Dodig-Ćurković14Tomislav Franić15Charlotte Gatherer16Elisa GhezaLidia ManentiAthanasios Maras17Francesco MargariAdriana PastoreMoli Paul18Diane Purper-Ouakil19Francesco RinaldiVehbi SakarGiulia Signorini20Cathy Street21Priya Tah22Sabine Tremmery23Amanda Tuffrey24Anna Wilson25Erika Riva26Renata NacinovichAlastair Canaway27Claire DaffernMarina Danckaerts28Frederique Bonnet-BrilhaultFrank C Verhulst29Emiliano MonzaniPaola Martinelli30Swaran P Singh31Ottaviano Martinelli32Gwen C Dieleman33James Griffin34Sonja AslanFrédérick Russet35James Kirwan36Ashley Liew37Véronique HumbertclaudeParamala J Santosh38Maria MigoneSuzanne E Gerritsen39Larissa S van Bodegom40Mathilde M Overbeek41Angelo Bertani42Maria G Cataldo43Patrizia Conti44David Da Fonseca45Cecilia Ferrari46Gaëlle Hendrickx47Alfred Kolozsvari48Flavia Micol Levi49Virginie Maurice50Lesley O'Hara51Veronique de Roeck52Melanie C Saam53Anne Sartor54Aurélie Schandrin55Ulrike M E Schulze56Elena Tanase57Therese A M J van Amelsvoort58Marco ArmandoNadia BaccanelliMonica BalaudoFabia BergamoJo BerrimanChrystèle Bodier RethoreAlbert BoonKaren BraamseUlrike BreuningerMaura ButtiglioneSarah ButtleMarco CammaranoFortunata CantiniCristiano CappellariMarta CareniniIsabelle CharvinKrizia ChianuraPhilippa ColemanAnnalisa ColonnaPatrizia ConeseRaffaella CostanzoPeter DineenJean-Pierre ErmansAlan FarmerJörg M FegertAlessandro FerrariSabrina FerrariGiuliana GaleaMichela GattaGiacomo GogliaMariaRosa GrandettoElaine HealyKeith HolmesNicola IngravalloRoberta InvernizziRenaud JardriCaoimhe KellyMeghan KillileaCatherine KlockaertsVlatka KovačHélène Lida-PulikChristel LippensFionnuala LynchFrancesca MacchiLeighton McFaddenDeny MenghiniGiorgia MoriniTodor MutafovCristina NegrinottiEmmanuel NelisFrancesca NeriPaulina NikolovaMarzia NossaMichele NoterdaemeFrancesca OpertoVittoria PanaroAesa ParentiVinuthna PemmarajuAnn PepermansAnna PresicciCatherine PrigentLaura RivoltaAnne RoekensBen RogersPablo RonziniSelena SalvettiTanveer SandhuRenate SchepkerPaolo Scocco59Marco SivieroMichael SlowikCourtney SmythMaria Antonietta SpadonePaolo StagiPamela StagniFabrizio Starace60Patrizia StoppaLucia TansiniCecilia ToselliGuido TrabucchiMaria TubitoArno van DamHanne Van GutschovenDirk van WestFabio VanniChiara VannicolaCristiana VaruzzaPamela VarvaraPatrizia VenturaStefano VicariStefania ViciniCarolin von BentzelBeata WilliamsMarina ZabarellaAnna ZamboniEdda Zanetti9 Department of Academic Child and Adolescent Psychiatry, University College Dublin, School of Medicine & Medical Science, Dublin, Ireland2 Warwick Medical School, University of Warwick, Coventry, UKRhode Island Department of Health, Providence, Rhode Island, USADepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UKDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UKWarwick Medical School, University of Warwick, Coventry, UK9 National Institute for Health and Care Research, Applied Research Collaboration (ARC) West Midlands, University of Warwick, Coventry, UKDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UKDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UKDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UKDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UK1 NIHR Mental Health Policy Research Unit, UCL, London, UKUniversity Hospital Center Split, Split, Croatia8 Unit of Epidemiological Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, ItalyFaculty for Dental Care and Health, Osijek, Croatia7 Department of Psychiatry, Clinical Hospital Center Split, Split, CroatiaWarwick Medical School, University of Warwick, Coventry, UK4 Yulius Academy, Yulius Mental Health Organization, Dordrecht, The NetherlandsWarwick Medical School, University of Warwick, Coventry, UKHôpital Saint Eloi, Médecine Psychologique de l’Enfant et de l’Adolescent, Centre Hospitalier Regional Universitaire de Montpellier, Montpellier, Languedoc-Roussillon, FranceIRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, ItalyWarwick Medical School, University of Warwick, Coventry, UKWarwick Medical School, University of Warwick, Coventry, UK15 Department of Neurosciences, KU Leuven, Leuven, BelgiumWarwick Medical School, University of Warwick, Coventry, UK2University of Glasgow Medical School, Glasgow, UK1 Service of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland2 Warwick Medical School, University of Warwick, Coventry, UKDevelopmental Psychiatry, UPC KU Leuven, Leuven, BelgiumDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus Medical Center, Rotterdam, The NetherlandsInstitute for Cancer Research, Comprehensive Cancer Center, Medizinische Universitat Wien, Wien, Austria2 Warwick Medical School, University of Warwick, Coventry, UKChild and Adolescent Neuropsychiatry Unit, ASST di Lecco, Lecco, ItalyDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus Medical Center, Rotterdam, The NetherlandsWarwick Clinical Trials Unit, University of Warwick, Coventry, UKCentre Hospitalier Universitaire de Montpellier, Saint Eloi Hospital, Montpellier, FrancePortsmouth Hospitals University NHS Trust3 Evelina London Children`s Hospital, King`s College London, London, UKDepartment of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King`s College London, London, UKDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus Medical Center, Rotterdam, The NetherlandsDepartment of Child and Adolescent Psychiatry and Psychology, Erasmus Medical Center, Rotterdam, The NetherlandsYulius Academy, Yulius Mental Health Organization, Dordrecht, The NetherlandsASST Santi Paolo e Carlo, Milano, ItalyIRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, ItalyASST Lariana, Como, ItalyCentre Hospitalier Universitaire de Marseille, Marseille, FranceTeenagers` Outpatient Unit, Child and Adolescent Mental Health Services, Niguarda Metropolitan Great Hospital, Milan, ItalyDepartment of Neurosciences, Centre for Clinical Psychiatry, KU Leuven, Leuven, BelgiumHealthTracker Ltd, Kent, UKIRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, ItalyCentre Hospitalier Universitaire de Montpellier, Saint Eloi Hospital, Montpellier, FranceSaint John of God Research Foundation, Dublin, IrelandDepartment of Neurosciences, Centre for Clinical Psychiatry, KU Leuven, Leuven, BelgiumDepartment of Child and Adolescent Psychiatry/Psychotherapy, University of Ulm, Ulm, GermanyJosefinum Augsburg, Klinik für Kinder- und Jugenspsychiatrie und Psychotherapie, Augsburg, GermanyCentre Hospitalier Universitaire de Montpellier, Saint Eloi Hospital, Montpellier, France13 Department of Child and Adolescent Psychiatry/Psychotherapy, Ulm University, Ulm, GermanyAbteilung für Psychiatrie und Psychotherapie des Kindes-und Jugendalters Weissenau, ZfP Südwürttemberg, Ravensburg, GermanyDepartment of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The NetherlandspsychiatristDepartment of Mental Health and Dependence, AUSL Modena, Modena, ItalyPurpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports.Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at.Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be ‘markedly ill’, ‘severely ill’ or ‘among the most extremely ill’ by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year.Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared.Trial registration number NCT03013595.https://bmjopen.bmj.com/content/11/12/e053373.full
spellingShingle Philip Wells
Andrea De Giacomo
Lucia Margari
Maria Giuseppina Petruzzelli
Fiona McNicholas
Helen Keeley
Mario Speranza
Giuseppe Carrà
Jason Madan
James McDonald
Jatinder Singh
Federico Fiori
Leanne Walker
Helena Tuomainen
Sarah Miller
Laura Adams
Mathilde Mastroianni
Natalie Heaney
Kate Lievesley
Ilyas Sagar-Ouriaghli
Giovanni Allibrio
Rebecca Appleton
Nikolina Davidović
Giovanni de Girolamo
Katarina Dodig-Ćurković
Tomislav Franić
Charlotte Gatherer
Elisa Gheza
Lidia Manenti
Athanasios Maras
Francesco Margari
Adriana Pastore
Moli Paul
Diane Purper-Ouakil
Francesco Rinaldi
Vehbi Sakar
Giulia Signorini
Cathy Street
Priya Tah
Sabine Tremmery
Amanda Tuffrey
Anna Wilson
Erika Riva
Renata Nacinovich
Alastair Canaway
Claire Daffern
Marina Danckaerts
Frederique Bonnet-Brilhault
Frank C Verhulst
Emiliano Monzani
Paola Martinelli
Swaran P Singh
Ottaviano Martinelli
Gwen C Dieleman
James Griffin
Sonja Aslan
Frédérick Russet
James Kirwan
Ashley Liew
Véronique Humbertclaude
Paramala J Santosh
Maria Migone
Suzanne E Gerritsen
Larissa S van Bodegom
Mathilde M Overbeek
Angelo Bertani
Maria G Cataldo
Patrizia Conti
David Da Fonseca
Cecilia Ferrari
Gaëlle Hendrickx
Alfred Kolozsvari
Flavia Micol Levi
Virginie Maurice
Lesley O'Hara
Veronique de Roeck
Melanie C Saam
Anne Sartor
Aurélie Schandrin
Ulrike M E Schulze
Elena Tanase
Therese A M J van Amelsvoort
Marco Armando
Nadia Baccanelli
Monica Balaudo
Fabia Bergamo
Jo Berriman
Chrystèle Bodier Rethore
Albert Boon
Karen Braamse
Ulrike Breuninger
Maura Buttiglione
Sarah Buttle
Marco Cammarano
Fortunata Cantini
Cristiano Cappellari
Marta Carenini
Isabelle Charvin
Krizia Chianura
Philippa Coleman
Annalisa Colonna
Patrizia Conese
Raffaella Costanzo
Peter Dineen
Jean-Pierre Ermans
Alan Farmer
Jörg M Fegert
Alessandro Ferrari
Sabrina Ferrari
Giuliana Galea
Michela Gatta
Giacomo Goglia
MariaRosa Grandetto
Elaine Healy
Keith Holmes
Nicola Ingravallo
Roberta Invernizzi
Renaud Jardri
Caoimhe Kelly
Meghan Killilea
Catherine Klockaerts
Vlatka Kovač
Hélène Lida-Pulik
Christel Lippens
Fionnuala Lynch
Francesca Macchi
Leighton McFadden
Deny Menghini
Giorgia Morini
Todor Mutafov
Cristina Negrinotti
Emmanuel Nelis
Francesca Neri
Paulina Nikolova
Marzia Nossa
Michele Noterdaeme
Francesca Operto
Vittoria Panaro
Aesa Parenti
Vinuthna Pemmaraju
Ann Pepermans
Anna Presicci
Catherine Prigent
Laura Rivolta
Anne Roekens
Ben Rogers
Pablo Ronzini
Selena Salvetti
Tanveer Sandhu
Renate Schepker
Paolo Scocco
Marco Siviero
Michael Slowik
Courtney Smyth
Maria Antonietta Spadone
Paolo Stagi
Pamela Stagni
Fabrizio Starace
Patrizia Stoppa
Lucia Tansini
Cecilia Toselli
Guido Trabucchi
Maria Tubito
Arno van Dam
Hanne Van Gutschoven
Dirk van West
Fabio Vanni
Chiara Vannicola
Cristiana Varuzza
Pamela Varvara
Patrizia Ventura
Stefano Vicari
Stefania Vicini
Carolin von Bentzel
Beata Williams
Marina Zabarella
Anna Zamboni
Edda Zanetti
Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe
BMJ Open
title Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe
title_full Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe
title_fullStr Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe
title_full_unstemmed Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe
title_short Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe
title_sort cohort profile demographic and clinical characteristics of the milestone longitudinal cohort of young people approaching the upper age limit of their child mental health care service in europe
url https://bmjopen.bmj.com/content/11/12/e053373.full
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AT fabriziostarace cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT patriziastoppa cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT luciatansini cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT ceciliatoselli cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT guidotrabucchi cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT mariatubito cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT arnovandam cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT hannevangutschoven cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT dirkvanwest cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT fabiovanni cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT chiaravannicola cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT cristianavaruzza cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT pamelavarvara cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT patriziaventura cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT stefanovicari cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT stefaniavicini cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT carolinvonbentzel cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT beatawilliams cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT marinazabarella cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT annazamboni cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope
AT eddazanetti cohortprofiledemographicandclinicalcharacteristicsofthemilestonelongitudinalcohortofyoungpeopleapproachingtheupperagelimitoftheirchildmentalhealthcareserviceineurope