A 3D SVZonChip Model for In Vitro Mimicry of the Subventricular Zone Neural Stem Cell Niche

A 3D SVZonChip Model for In Vitro Mimicry of the Subventricular Zone Neural Stem Cell Niche

Neural stem cells (NSCs) are crucial components of the nervous system, primarily located in the subventricular zone (SVZ) and subgranular zone (SGZ). The SVZ neural stem cell niche (NSCN) is a specialized microenvironment where growth factors and extracellular matrix (ECM) components collaborate to...

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Bibliographic Details
Main Authors: Ioannis Angelopoulos, Konstantinos Ioannidis, Konstantina Gr. Lyroni, Dimitris Vlassopoulos, Martina Samiotaki, Eleni Pavlidou, Xanthippi Chatzistavrou, Ioannis Papantoniou, Konstantinos Papageorgiou, Spyridon K. Kritas, Ioannis Grivas
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Bioengineering
Subjects:
subventricular zone (SVZ)
neural stem cells (NSCs)
3D organotypic in vitro culture
organ on a chip (OCC)
microfluidics
biofabrication
Online Access:https://www.mdpi.com/2306-5354/12/6/562
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