Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood
Diverse virulence genes encode for the Type III secretion system (T3SS) in bacteria. In Salmonella, these genes are located in the Salmonella pathogenicity Islands 1 and 2 (SPI-1 and SPI-2), and they facilitate bacterial invasion and replication within macrophages, contributing to the burden of nont...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/jotm/1139253 |
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| author | Yemisi Olukemi Adesiji Vijaya Kumar Deekshit Rasheed A. Odunola Indrani Karunasagar Oluwafemi B. Daodu Al-Mustapha Ahmad |
| author_facet | Yemisi Olukemi Adesiji Vijaya Kumar Deekshit Rasheed A. Odunola Indrani Karunasagar Oluwafemi B. Daodu Al-Mustapha Ahmad |
| author_sort | Yemisi Olukemi Adesiji |
| collection | DOAJ |
| description | Diverse virulence genes encode for the Type III secretion system (T3SS) in bacteria. In Salmonella, these genes are located in the Salmonella pathogenicity Islands 1 and 2 (SPI-1 and SPI-2), and they facilitate bacterial invasion and replication within macrophages, contributing to the burden of nontyphoidal Salmonella infections. In this study, we investigated the prevalence of selected virulence-encoding genes in 30 laboratory stocks of Salmonella enterica serovar Enteritidis from Nigeria (16 isolates) and nonclinical sources comprising poultry and seafood from India (14 isolates). Analysis of PCR amplicons revealed that the genes sseB, sseD, sseF, sseT, and invH were conserved in all the isolates except for two isolates obtained from clams, which did not have the sseD and sseF genes. In addition, the sseC and sseG genes were absent from all the tested isolates. This study provides insights into the distribution of selected T3SS genes among Salmonella spp. isolated from clinical and raw animal food sources in Nigeria and India, respectively. |
| format | Article |
| id | doaj-art-e2728ed9a8264b889bb97f7576521658 |
| institution | Kabale University |
| issn | 1687-9694 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-e2728ed9a8264b889bb97f75765216582025-08-20T03:49:55ZengWileyJournal of Tropical Medicine1687-96942025-01-01202510.1155/jotm/1139253Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and SeafoodYemisi Olukemi Adesiji0Vijaya Kumar Deekshit1Rasheed A. Odunola2Indrani Karunasagar3Oluwafemi B. Daodu4Al-Mustapha Ahmad5Department of Medical Microbiology and ParasitologyDepartment of Infectious Disease and Microbial GenomicsUniversity Health ServicesDepartment of MicrobiologyDepartment of Veterinary MicrobiologyDepartment of Veterinary Public Health and Preventive MedicineDiverse virulence genes encode for the Type III secretion system (T3SS) in bacteria. In Salmonella, these genes are located in the Salmonella pathogenicity Islands 1 and 2 (SPI-1 and SPI-2), and they facilitate bacterial invasion and replication within macrophages, contributing to the burden of nontyphoidal Salmonella infections. In this study, we investigated the prevalence of selected virulence-encoding genes in 30 laboratory stocks of Salmonella enterica serovar Enteritidis from Nigeria (16 isolates) and nonclinical sources comprising poultry and seafood from India (14 isolates). Analysis of PCR amplicons revealed that the genes sseB, sseD, sseF, sseT, and invH were conserved in all the isolates except for two isolates obtained from clams, which did not have the sseD and sseF genes. In addition, the sseC and sseG genes were absent from all the tested isolates. This study provides insights into the distribution of selected T3SS genes among Salmonella spp. isolated from clinical and raw animal food sources in Nigeria and India, respectively.http://dx.doi.org/10.1155/jotm/1139253 |
| spellingShingle | Yemisi Olukemi Adesiji Vijaya Kumar Deekshit Rasheed A. Odunola Indrani Karunasagar Oluwafemi B. Daodu Al-Mustapha Ahmad Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood Journal of Tropical Medicine |
| title | Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood |
| title_full | Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood |
| title_fullStr | Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood |
| title_full_unstemmed | Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood |
| title_short | Virulence-Encoding Genes Conserved in Salmonella Isolated From Humans, Poultry, and Seafood |
| title_sort | virulence encoding genes conserved in salmonella isolated from humans poultry and seafood |
| url | http://dx.doi.org/10.1155/jotm/1139253 |
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