Neurocysticercosis as a probable risk factor for hippocampal sclerosis
ABSTRACT Neurocysticercosis is one of the most common risk factors for epilepsy but its association with drug-resistant epilepsy remains uncertain. Conjectures of an association with drug-resistant epilepsy have been fueled by reports of an association between calcific neurocysticercosis lesions (CN...
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001100783&lng=en&tlng=en |
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| author | Gagandeep Singh Josemir W. Sander |
| author_facet | Gagandeep Singh Josemir W. Sander |
| author_sort | Gagandeep Singh |
| collection | DOAJ |
| description | ABSTRACT Neurocysticercosis is one of the most common risk factors for epilepsy but its association with drug-resistant epilepsy remains uncertain. Conjectures of an association with drug-resistant epilepsy have been fueled by reports of an association between calcific neurocysticercosis lesions (CNL) and hippocampal sclerosis (HS) from specialized epilepsy centers in Taenia solium-endemic regions. The debate arising from these reports is whether the association is causal. Evidence for the association is not high quality but sufficiently persuasive to merit further investigation with longitudinal imaging studies in population-based samples from geographically-diverse regions. The other controversial point is the choice of a surgical approach for drug-resistant epilepsy associated with CNL-HS. Three approaches have been described: standard anteromesial temporal lobectomy, lesionectomy involving a CNL alone and lesionectomy with anteromesial temporal lobectomy (for dual pathology); reports of the latter two approaches are limited. Presurgical evaluation should consider possibilities of delineating the epileptogenic zone/s in accordance with all three approaches. |
| format | Article |
| id | doaj-art-e26ec98ff05f4fb5b8cab9b1d1bb9889 |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-e26ec98ff05f4fb5b8cab9b1d1bb98892025-08-20T02:21:14ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-4227761178379010.1590/0004-282x20180130S0004-282X2018001100783Neurocysticercosis as a probable risk factor for hippocampal sclerosisGagandeep SinghJosemir W. SanderABSTRACT Neurocysticercosis is one of the most common risk factors for epilepsy but its association with drug-resistant epilepsy remains uncertain. Conjectures of an association with drug-resistant epilepsy have been fueled by reports of an association between calcific neurocysticercosis lesions (CNL) and hippocampal sclerosis (HS) from specialized epilepsy centers in Taenia solium-endemic regions. The debate arising from these reports is whether the association is causal. Evidence for the association is not high quality but sufficiently persuasive to merit further investigation with longitudinal imaging studies in population-based samples from geographically-diverse regions. The other controversial point is the choice of a surgical approach for drug-resistant epilepsy associated with CNL-HS. Three approaches have been described: standard anteromesial temporal lobectomy, lesionectomy involving a CNL alone and lesionectomy with anteromesial temporal lobectomy (for dual pathology); reports of the latter two approaches are limited. Presurgical evaluation should consider possibilities of delineating the epileptogenic zone/s in accordance with all three approaches.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001100783&lng=en&tlng=enEpilepsia resistente a medicamentosneurocisticercoseepilepsia |
| spellingShingle | Gagandeep Singh Josemir W. Sander Neurocysticercosis as a probable risk factor for hippocampal sclerosis Arquivos de Neuro-Psiquiatria Epilepsia resistente a medicamentos neurocisticercose epilepsia |
| title | Neurocysticercosis as a probable risk factor for hippocampal sclerosis |
| title_full | Neurocysticercosis as a probable risk factor for hippocampal sclerosis |
| title_fullStr | Neurocysticercosis as a probable risk factor for hippocampal sclerosis |
| title_full_unstemmed | Neurocysticercosis as a probable risk factor for hippocampal sclerosis |
| title_short | Neurocysticercosis as a probable risk factor for hippocampal sclerosis |
| title_sort | neurocysticercosis as a probable risk factor for hippocampal sclerosis |
| topic | Epilepsia resistente a medicamentos neurocisticercose epilepsia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018001100783&lng=en&tlng=en |
| work_keys_str_mv | AT gagandeepsingh neurocysticercosisasaprobableriskfactorforhippocampalsclerosis AT josemirwsander neurocysticercosisasaprobableriskfactorforhippocampalsclerosis |