From the Gut to the Liver: Another Organ to Watch in FAP Patients
We report a rare association of hepatocellular carcinoma with familial adenomatous polyposis in a young patient and its clinical significance. A 28-year-old female with a past medical history of familial adenomatous polyposis (FAP) and subsequent colonic adenocarcinoma underwent total colectomy. She...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2016/1738696 |
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| _version_ | 1850167202017181696 |
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| author | Spencer Paulson Charmi Patel Hitendra Patel |
| author_facet | Spencer Paulson Charmi Patel Hitendra Patel |
| author_sort | Spencer Paulson |
| collection | DOAJ |
| description | We report a rare association of hepatocellular carcinoma with familial adenomatous polyposis in a young patient and its clinical significance. A 28-year-old female with a past medical history of familial adenomatous polyposis (FAP) and subsequent colonic adenocarcinoma underwent total colectomy. She later presented with intermittent right upper quadrant pain and nausea of four months’ duration. MRI of the abdomen revealed multiple liver lesions, the largest 8.5 cm in diameter, with radiologic features suggestive of hepatocellular carcinoma. A CT-guided liver biopsy demonstrated well-differentiated HCC which was confirmed by immunohistochemistry. In patients with a history of FAP, a heightened awareness of the possibility of concurrent or subsequent HCC is warranted. |
| format | Article |
| id | doaj-art-e26bff43c3db4fdb91bf5d85dbca39a6 |
| institution | OA Journals |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-e26bff43c3db4fdb91bf5d85dbca39a62025-08-20T02:21:14ZengWileyCase Reports in Pathology2090-67812090-679X2016-01-01201610.1155/2016/17386961738696From the Gut to the Liver: Another Organ to Watch in FAP PatientsSpencer Paulson0Charmi Patel1Hitendra Patel2Department of Pathology, University of Arizona, Tucson, AZ 85724, USADepartment of Pathology, University of Arizona, Tucson, AZ 85724, USASection of Hematology and Oncology, University of Arizona, Tucson, AZ 85724, USAWe report a rare association of hepatocellular carcinoma with familial adenomatous polyposis in a young patient and its clinical significance. A 28-year-old female with a past medical history of familial adenomatous polyposis (FAP) and subsequent colonic adenocarcinoma underwent total colectomy. She later presented with intermittent right upper quadrant pain and nausea of four months’ duration. MRI of the abdomen revealed multiple liver lesions, the largest 8.5 cm in diameter, with radiologic features suggestive of hepatocellular carcinoma. A CT-guided liver biopsy demonstrated well-differentiated HCC which was confirmed by immunohistochemistry. In patients with a history of FAP, a heightened awareness of the possibility of concurrent or subsequent HCC is warranted.http://dx.doi.org/10.1155/2016/1738696 |
| spellingShingle | Spencer Paulson Charmi Patel Hitendra Patel From the Gut to the Liver: Another Organ to Watch in FAP Patients Case Reports in Pathology |
| title | From the Gut to the Liver: Another Organ to Watch in FAP Patients |
| title_full | From the Gut to the Liver: Another Organ to Watch in FAP Patients |
| title_fullStr | From the Gut to the Liver: Another Organ to Watch in FAP Patients |
| title_full_unstemmed | From the Gut to the Liver: Another Organ to Watch in FAP Patients |
| title_short | From the Gut to the Liver: Another Organ to Watch in FAP Patients |
| title_sort | from the gut to the liver another organ to watch in fap patients |
| url | http://dx.doi.org/10.1155/2016/1738696 |
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