Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement

Thromboprophylaxis are routinely given to prevent venous thromboembolism (VTE) in patients after total hip and knee replacement surgeries. Low molecular weight heparin (LMWH) (fractioned heparin) is effective in the prevention and treatment of VTE. The predicable effect of LMWH has popularized it fo...

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Main Authors: S. V. Karuppiah, A. J. Johnstone
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2014/139218
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author S. V. Karuppiah
A. J. Johnstone
author_facet S. V. Karuppiah
A. J. Johnstone
author_sort S. V. Karuppiah
collection DOAJ
description Thromboprophylaxis are routinely given to prevent venous thromboembolism (VTE) in patients after total hip and knee replacement surgeries. Low molecular weight heparin (LMWH) (fractioned heparin) is effective in the prevention and treatment of VTE. The predicable effect of LMWH has popularized it for routine clinical use. Although LMWH has lesser complication rate, compared to unfractioned heparin (UFH), sporadic clinical complication has been reported. We report a rare case of skin necrosis secondary to use of LMWH tinzaparin used for routine thromboprophylaxis after total knee replacement.
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institution Kabale University
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spelling doaj-art-e26bce112f674f6facf5ad18462b0cfc2025-02-03T05:46:27ZengWileyCase Reports in Orthopedics2090-67492090-67572014-01-01201410.1155/2014/139218139218Skin Necrosis Associated with Thromboprophylaxis after Total Knee ReplacementS. V. Karuppiah0A. J. Johnstone1Department of Trauma & Orthopaedics, Grampian University Hospitals NHS Trust, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UKDepartment of Trauma & Orthopaedics, Grampian University Hospitals NHS Trust, Aberdeen Royal Infirmary, Aberdeen AB25 2ZN, UKThromboprophylaxis are routinely given to prevent venous thromboembolism (VTE) in patients after total hip and knee replacement surgeries. Low molecular weight heparin (LMWH) (fractioned heparin) is effective in the prevention and treatment of VTE. The predicable effect of LMWH has popularized it for routine clinical use. Although LMWH has lesser complication rate, compared to unfractioned heparin (UFH), sporadic clinical complication has been reported. We report a rare case of skin necrosis secondary to use of LMWH tinzaparin used for routine thromboprophylaxis after total knee replacement.http://dx.doi.org/10.1155/2014/139218
spellingShingle S. V. Karuppiah
A. J. Johnstone
Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement
Case Reports in Orthopedics
title Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement
title_full Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement
title_fullStr Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement
title_full_unstemmed Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement
title_short Skin Necrosis Associated with Thromboprophylaxis after Total Knee Replacement
title_sort skin necrosis associated with thromboprophylaxis after total knee replacement
url http://dx.doi.org/10.1155/2014/139218
work_keys_str_mv AT svkaruppiah skinnecrosisassociatedwiththromboprophylaxisaftertotalkneereplacement
AT ajjohnstone skinnecrosisassociatedwiththromboprophylaxisaftertotalkneereplacement