Renal intercalated cells sense and mediate inflammation via the P2Y14 receptor.

Renal intercalated cells sense and mediate inflammation via the P2Y14 receptor.

Uncontrolled inflammation is one of the leading causes of kidney failure. Pro-inflammatory responses can occur in the absence of infection, a process called sterile inflammation. Here we show that the purinergic receptor P2Y14 (GPR105) is specifically and highly expressed in collecting duct intercal...

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Bibliographic Details
Main Authors: Anie Azroyan, Virna Cortez-Retamozo, Richard Bouley, Rachel Liberman, Ye Chun Ruan, Evgeny Kiselev, Kenneth A Jacobson, Mikael J Pittet, Dennis Brown, Sylvie Breton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0121419&type=printable
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