ABCA1 Deletion Does Not Affect Aqueous Humor Outflow Function in Mice

Background. ATP binding cassette transporter A1 (ABCA1) is a candidate gene within a POAG susceptibility locus by GWAS analysis, and it is involved in IOP modulation via the Cav1/eNOS/NO signaling pathway. We aim to examine the phenotype of ABCA1 deletion in the ABCA1 gene knockout (Abca1−/−) mice....

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Bibliographic Details
Main Authors: Bo Qin, Chunchun Hu, Youjia Zhang, Yuhong Chen, Yuan Lei
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2024/7195550
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