The effect of androgen blockade on [68Ga]Ga-PSMA-11 and [18F]FDG PET uptake in patients with recurrent or metastatic salivary duct carcinoma: a prospective imaging study

The effect of androgen blockade on [68Ga]Ga-PSMA-11 and [18F]FDG PET uptake in patients with recurrent or metastatic salivary duct carcinoma: a prospective imaging study

Abstract Background The expression of prostate-specific membrane antigen (PSMA), a target for oncological imaging and treatment, is upregulated by androgen blockade in prostate cancer. Salivary duct carcinoma (SDC), an aggressive histological subtype of salivary gland cancer, resembles prostate canc...

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Main Authors: Niels J. van Ruitenbeek, Maike J. M. Uijen, Chantal M. L. Driessen, Maartje C. van Rijk, Steffie M. B. Peters, Bastiaan M. Privé, Gerald W. Verhaegh, Adriana C. H. van Engen-van Grunsven, Martin Gotthardt, James Nagarajah, Carla M. L. van Herpen
Format: Article
Language:English
Published: SpringerOpen 2025-07-01
Series:EJNMMI Research
Subjects:
[18F]FDG
Androgen deprivation therapy
Positron emission tomography
Prostate-specific membrane antigen
Salivary duct carcinoma
Salivary gland cancer
Online Access:https://doi.org/10.1186/s13550-025-01275-x
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