Dentate line invasion is a risk factor for locoregional recurrence and distant metastasis following abdominoperineal resection in rectal cancer: a single-centre retrospective cohort study based on 1854 cases

Dentate line invasion is a risk factor for locoregional recurrence and distant metastasis following abdominoperineal resection in rectal cancer: a single-centre retrospective cohort study based on 1854 cases

Abstract Background In the context of surgical treatment for rectal cancer, the dentate line is acknowledged as a critical anatomical landmark. However, the prognostic implications of dentate line invasion (DLI) remain elusive and warrant further investigation. This study aims to evaluate and compar...

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Bibliographic Details
Main Authors: Zixing Zhu, Dedi Jiang, Yujuan Jiang, Jichuan Quan, Mingguang Zhang, Wei Pei, Jianjun Bi, Qiang Feng, Haitao Zhou, Zheng Wang, Zhaoxu Zheng, Qian Liu, Zhixun Zhao, Jianwei Liang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Cancer
Subjects:
Rectal cancer
Dentate line invasion
Abdominoperineal resection
Recurrence
Metastasis
Online Access:https://doi.org/10.1186/s12885-025-14001-6
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