Gut mycobiome maturation and its determinants during early childhood: a comparison of ITS2 amplicon and shotgun metagenomic sequencing approaches

Gut mycobiome maturation and its determinants during early childhood: a comparison of ITS2 amplicon and shotgun metagenomic sequencing approaches

IntroductionMicrobial colonization of the gut in early life is important for the development of metabolism, immunity, and the brain. Fungi and bacteria both colonize the human infant gut. The relatively smaller contribution of fungi to the gut microbiome, as compared to bacteria, has posed technical...

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Bibliographic Details
Main Authors: Timothy Heisel, Sara Gonia, Abrielle Dillon, Susan L. Hoops, Gabriel A. Al-Ghalith, Daryl Gohl, Sagori Mukhopadhyay, Karen Puopolo, Peter Kennedy, Michael J. Sadowsky, Dan Knights, Abigail J. Johnson, Jeffrey S. Gerber, Cheryl A. Gale
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Microbiology
Subjects:
gut mycobiome
childhood
ITS2 amplicon
whole genome shotgun metagenomics
longitudinal variation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1539750/full
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