Paper-based analytical devices for smart foodborne pathogen detection
Food safety continues to be a critical global challenge, with foodborne pathogens posing significant risks to public health and economic stability. The rapid detection of these pathogens, especially in resource-limited settings, is essential to mitigate outbreaks and enhance food safety systems. Thi...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-12-01
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| Series: | Talanta Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666831925001134 |
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| author | Hadeer M. Bedair Mohamed Emara Tamer M. Samir Mahmoud A.F. Khalil Shima Mahmoud Ali Mahmoud Hamed Fotouh R. Mansour |
| author_facet | Hadeer M. Bedair Mohamed Emara Tamer M. Samir Mahmoud A.F. Khalil Shima Mahmoud Ali Mahmoud Hamed Fotouh R. Mansour |
| author_sort | Hadeer M. Bedair |
| collection | DOAJ |
| description | Food safety continues to be a critical global challenge, with foodborne pathogens posing significant risks to public health and economic stability. The rapid detection of these pathogens, especially in resource-limited settings, is essential to mitigate outbreaks and enhance food safety systems. This review explores the advancements in paper-based analytical devices (PADs) as a practical, cost-effective, and portable solution for the detection of foodborne pathogens. Various detection platforms, including nucleic acid-based sensors, aptamer-integrated systems, Immunochromatographic assays, and nanoparticle-enhanced biosensors, are evaluated for their effectiveness in rapid and on-site testing. PADs meet the key requirements for point-of-need testing, including simplicity, speed, affordability, and versatility. Their ability to integrate with modern technologies such as smartphones and machine learning enhances their analytical performance and accessibility. Despite their promise, challenges remain, including sensitivity limitations and scalability. Addressing these gaps could unlock the full potential of PADs for widespread use in food safety monitoring and pathogen detection. |
| format | Article |
| id | doaj-art-e24d92f1414e4c8ab5afb66be57a00ea |
| institution | Kabale University |
| issn | 2666-8319 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Talanta Open |
| spelling | doaj-art-e24d92f1414e4c8ab5afb66be57a00ea2025-08-20T03:51:25ZengElsevierTalanta Open2666-83192025-12-011210051110.1016/j.talo.2025.100511Paper-based analytical devices for smart foodborne pathogen detectionHadeer M. Bedair0Mohamed Emara1Tamer M. Samir2Mahmoud A.F. Khalil3Shima Mahmoud Ali4Mahmoud Hamed5Fotouh R. Mansour6Department of Microbiology and Immunology, College of Pharmaceutical sciences and drug manufacturing, Misr University for Science and Technology, 12566, EgyptDepartment of Microbiology and Immunology, Faculty of Pharmacy, Helwan University Ain Helwan, Helwan, 11795, EgyptDepartment of Microbiology and Immunology, College of Pharmaceutical sciences and drug manufacturing, Misr University for Science and Technology, 12566, EgyptDepartment of Microbiology and Immunology, Faculty of Pharmacy, Fayoum University, 63514, EgyptDepartment of Microbiology and Immunology, Faculty of Pharmacy, Helwan University Ain Helwan, Helwan, 11795, EgyptPharmaceutical Chemistry Department, Faculty of Pharmacy, Misr International University, Km 28 Ismailia Road, Cairo 44971, Egypt; MIU Chemistry Society (MIU-CS), Faculty of Pharmacy, Misr International University, Km 28 Ismailia Road, Cairo 44971, EgyptPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Tanta University, Tanta 31111, Egypt; Department of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt; Corresponding author at: Elgeish Street, the medical campus of Tanta University, Tanta 31111, Egypt.Food safety continues to be a critical global challenge, with foodborne pathogens posing significant risks to public health and economic stability. The rapid detection of these pathogens, especially in resource-limited settings, is essential to mitigate outbreaks and enhance food safety systems. This review explores the advancements in paper-based analytical devices (PADs) as a practical, cost-effective, and portable solution for the detection of foodborne pathogens. Various detection platforms, including nucleic acid-based sensors, aptamer-integrated systems, Immunochromatographic assays, and nanoparticle-enhanced biosensors, are evaluated for their effectiveness in rapid and on-site testing. PADs meet the key requirements for point-of-need testing, including simplicity, speed, affordability, and versatility. Their ability to integrate with modern technologies such as smartphones and machine learning enhances their analytical performance and accessibility. Despite their promise, challenges remain, including sensitivity limitations and scalability. Addressing these gaps could unlock the full potential of PADs for widespread use in food safety monitoring and pathogen detection.http://www.sciencedirect.com/science/article/pii/S2666831925001134Paper-based analytical devicesFoodborne pathogen detectionContaminationPoint-of-use testingSmart phone |
| spellingShingle | Hadeer M. Bedair Mohamed Emara Tamer M. Samir Mahmoud A.F. Khalil Shima Mahmoud Ali Mahmoud Hamed Fotouh R. Mansour Paper-based analytical devices for smart foodborne pathogen detection Talanta Open Paper-based analytical devices Foodborne pathogen detection Contamination Point-of-use testing Smart phone |
| title | Paper-based analytical devices for smart foodborne pathogen detection |
| title_full | Paper-based analytical devices for smart foodborne pathogen detection |
| title_fullStr | Paper-based analytical devices for smart foodborne pathogen detection |
| title_full_unstemmed | Paper-based analytical devices for smart foodborne pathogen detection |
| title_short | Paper-based analytical devices for smart foodborne pathogen detection |
| title_sort | paper based analytical devices for smart foodborne pathogen detection |
| topic | Paper-based analytical devices Foodborne pathogen detection Contamination Point-of-use testing Smart phone |
| url | http://www.sciencedirect.com/science/article/pii/S2666831925001134 |
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