Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia
Reactive granulomatous dermatitis (RGD) is an umbrella term to describe a reaction pattern characterized by skin-colored to erythematous papules, plaques, and nodules although other morphologies have been described. RGD has rarely been reported in children, and in this report, we present the case of...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-01-01
|
| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2023/3428162 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849691573921513472 |
|---|---|
| author | Hannah C. Tolson Mariana McCune Miranda Yousif David DiCaudo Elizabeth Dupuy |
| author_facet | Hannah C. Tolson Mariana McCune Miranda Yousif David DiCaudo Elizabeth Dupuy |
| author_sort | Hannah C. Tolson |
| collection | DOAJ |
| description | Reactive granulomatous dermatitis (RGD) is an umbrella term to describe a reaction pattern characterized by skin-colored to erythematous papules, plaques, and nodules although other morphologies have been described. RGD has rarely been reported in children, and in this report, we present the case of a 3-year-old girl with acute lymphoblastic leukemia (ALL) who presented with firm, tender nodules, and ulcerated plaques on her extremities. Histopathologic examination showed foci of dense granulomatous inflammatory infiltrates composed of histiocytes, neutrophils, and multinucleate giant cells. The constellation of clinical symptoms, negative infectious workup, and histopathology support the diagnosis of RGD. |
| format | Article |
| id | doaj-art-e24a7853b7bb409dbdfc29003fe3063c |
| institution | DOAJ |
| issn | 2090-6471 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-e24a7853b7bb409dbdfc29003fe3063c2025-08-20T03:20:59ZengWileyCase Reports in Dermatological Medicine2090-64712023-01-01202310.1155/2023/3428162Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic LeukemiaHannah C. Tolson0Mariana McCune1Miranda Yousif2David DiCaudo3Elizabeth Dupuy4University of Arizona College of Medicine PhoenixUniversity of Arizona College of Medicine PhoenixUniversity of Arizona College of Medicine PhoenixMayo Clinic ScottsdalePhoenix Children’s HospitalReactive granulomatous dermatitis (RGD) is an umbrella term to describe a reaction pattern characterized by skin-colored to erythematous papules, plaques, and nodules although other morphologies have been described. RGD has rarely been reported in children, and in this report, we present the case of a 3-year-old girl with acute lymphoblastic leukemia (ALL) who presented with firm, tender nodules, and ulcerated plaques on her extremities. Histopathologic examination showed foci of dense granulomatous inflammatory infiltrates composed of histiocytes, neutrophils, and multinucleate giant cells. The constellation of clinical symptoms, negative infectious workup, and histopathology support the diagnosis of RGD.http://dx.doi.org/10.1155/2023/3428162 |
| spellingShingle | Hannah C. Tolson Mariana McCune Miranda Yousif David DiCaudo Elizabeth Dupuy Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia Case Reports in Dermatological Medicine |
| title | Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia |
| title_full | Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia |
| title_fullStr | Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia |
| title_full_unstemmed | Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia |
| title_short | Reactive Granulomatous Dermatitis in a Child with Acute Lymphoblastic Leukemia |
| title_sort | reactive granulomatous dermatitis in a child with acute lymphoblastic leukemia |
| url | http://dx.doi.org/10.1155/2023/3428162 |
| work_keys_str_mv | AT hannahctolson reactivegranulomatousdermatitisinachildwithacutelymphoblasticleukemia AT marianamccune reactivegranulomatousdermatitisinachildwithacutelymphoblasticleukemia AT mirandayousif reactivegranulomatousdermatitisinachildwithacutelymphoblasticleukemia AT daviddicaudo reactivegranulomatousdermatitisinachildwithacutelymphoblasticleukemia AT elizabethdupuy reactivegranulomatousdermatitisinachildwithacutelymphoblasticleukemia |