Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care

Skin wound management is a very difficult undertaking in the medical field. There is no information available concerning the wound beneath the bandages. Electrospun nanofibrous wound dressings stand out for their resemblance to extracellular matrix (ECM), increased surface-to-volume ratio, porousnes...

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Main Authors: Biruk Fentahun Adamu, Jing Gao, Esubalew Kasaw Gebeyehu, Kura Alemayehu Beyene, Melkie Getnet Tadesse, Erkihun Zelalem Liyew
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2022/2025170
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author Biruk Fentahun Adamu
Jing Gao
Esubalew Kasaw Gebeyehu
Kura Alemayehu Beyene
Melkie Getnet Tadesse
Erkihun Zelalem Liyew
author_facet Biruk Fentahun Adamu
Jing Gao
Esubalew Kasaw Gebeyehu
Kura Alemayehu Beyene
Melkie Getnet Tadesse
Erkihun Zelalem Liyew
author_sort Biruk Fentahun Adamu
collection DOAJ
description Skin wound management is a very difficult undertaking in the medical field. There is no information available concerning the wound beneath the bandages. Electrospun nanofibrous wound dressings stand out for their resemblance to extracellular matrix (ECM), increased surface-to-volume ratio, porousness, and capacity to encapsulate or load medications, among other distinctive qualities. Traditional antibacterial loaded electrospun nanofibrous wound dressings do not indicate the state of the wound and constantly release antibacterial chemicals even when there are no bacteria in the wound area. As a result, dressings that can track the condition of the wound and dispense medications as needed are crucial. Self-responsive wound dressings can release medications based on bacterial, oxygen spectra, pH, or infection responsiveness, reducing the need for antibacterial agents. Self-responsive mats, which are wound dressings that can release medications based on response to bacteria, oxygen species, and pH or infections, are required to reduce the overuse of antibacterial agents. Self-responsive electrospun nanofibrous mats can be used to monitor the condition of a wound by altering its color in response to an infection or a change in the pH of the wound. Electrospun nanofibrous wound dressings that are stimulus-responsive (self-responsive) are discussed in this review paper. Self-responsive electrospun nanofibrous wound dressings that are triggered by pH, temperature, light, bacteria, and oxygen species are discussed in detail after self-responsive smart materials or polymers used for electrospun nanofibrous wound dressings are covered in the first section of the review.
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spelling doaj-art-e243f8b5aa294c08ad877b61cd0ed7272025-02-03T01:00:45ZengWileyAdvances in Materials Science and Engineering1687-84422022-01-01202210.1155/2022/2025170Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound CareBiruk Fentahun Adamu0Jing Gao1Esubalew Kasaw Gebeyehu2Kura Alemayehu Beyene3Melkie Getnet Tadesse4Erkihun Zelalem Liyew5College of TextilesCollege of TextilesTextile Chemical Process Engineering DepartmentTextile Engineering DepartmentTextile Chemical Process Engineering DepartmentTextile Engineering DepartmentSkin wound management is a very difficult undertaking in the medical field. There is no information available concerning the wound beneath the bandages. Electrospun nanofibrous wound dressings stand out for their resemblance to extracellular matrix (ECM), increased surface-to-volume ratio, porousness, and capacity to encapsulate or load medications, among other distinctive qualities. Traditional antibacterial loaded electrospun nanofibrous wound dressings do not indicate the state of the wound and constantly release antibacterial chemicals even when there are no bacteria in the wound area. As a result, dressings that can track the condition of the wound and dispense medications as needed are crucial. Self-responsive wound dressings can release medications based on bacterial, oxygen spectra, pH, or infection responsiveness, reducing the need for antibacterial agents. Self-responsive mats, which are wound dressings that can release medications based on response to bacteria, oxygen species, and pH or infections, are required to reduce the overuse of antibacterial agents. Self-responsive electrospun nanofibrous mats can be used to monitor the condition of a wound by altering its color in response to an infection or a change in the pH of the wound. Electrospun nanofibrous wound dressings that are stimulus-responsive (self-responsive) are discussed in this review paper. Self-responsive electrospun nanofibrous wound dressings that are triggered by pH, temperature, light, bacteria, and oxygen species are discussed in detail after self-responsive smart materials or polymers used for electrospun nanofibrous wound dressings are covered in the first section of the review.http://dx.doi.org/10.1155/2022/2025170
spellingShingle Biruk Fentahun Adamu
Jing Gao
Esubalew Kasaw Gebeyehu
Kura Alemayehu Beyene
Melkie Getnet Tadesse
Erkihun Zelalem Liyew
Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care
Advances in Materials Science and Engineering
title Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care
title_full Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care
title_fullStr Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care
title_full_unstemmed Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care
title_short Self-Responsive Electrospun Nanofibers Wound Dressings: The Future of Wound Care
title_sort self responsive electrospun nanofibers wound dressings the future of wound care
url http://dx.doi.org/10.1155/2022/2025170
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