PIK3CA gene mutation status associated with poor prognosis of breast cancer: a retrospective cohort study

PIK3CA gene mutation status associated with poor prognosis of breast cancer: a retrospective cohort study

Abstract Purpose PIK3CA gene mutations have been identified in various malignancies, but the prevalence of specific mutations and their role in breast cancer development remain uncertain. This study aimed to investigate the clinicopathological significance and prognostic impact of PIK3CA mutations i...

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Bibliographic Details
Main Authors: Min Yan, Zhiqiang Zong, Wenyue Guo, Xinyu Li, Jingjing Li, Xi Xia, Xiaolei Wang, Yuan Kong, Fanfan Li
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Cancer
Subjects:
PIK3CA
H1047R mutation
Breast cancer
Poor survival
Online Access:https://doi.org/10.1186/s12885-025-13486-5
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