Growth differentiation factor 10 inhibits fat infiltration in tongue muscles of mice with high-fat diet

Growth differentiation factor 10 inhibits fat infiltration in tongue muscles of mice with high-fat diet

Abstract Background Tongue muscles contain a much greater number of residual adipocytes than other muscles do, which makes them susceptible to obesity-induced muscle fat remodeling. Tongue fat remodeling leads to obesity-induced obstructive sleep apnea (OSA), which is a common sleep disorder charact...

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Bibliographic Details
Main Authors: Seunghyun A. Kim, Christina Xu, Kyungmin Kim, Xiaoxing Xu, Yufei Du, Hyojung J. Choo
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Skeletal Muscle
Subjects:
Tongue muscle
Fibroadipose progenitors
Denervation
Obesity
High-fat diet
Growth differentiation factor 10
Online Access:https://doi.org/10.1186/s13395-025-00389-z
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