TNF-α Promotes the Recovery of Dorsal Root Ganglion Neurons from Cisplatin-Induced Injury Through an NGF-Independent Mechanism

TNF-α Promotes the Recovery of Dorsal Root Ganglion Neurons from Cisplatin-Induced Injury Through an NGF-Independent Mechanism

Nerve injury caused by chemotherapy drugs is a common side effect. How to reduce this kind of nerve injury and promote neuron recovery is of great significance. In this study, we found that tumor necrosis factor-α (TNF-α) promoted the recovery of dorsal root ganglion (DRG) neuron from cisplatin-indu...

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Bibliographic Details
Main Authors: Yiling Wei, Xianlin Xu, Pan Wu, Xiang Chen, Qingmei Mo, Ming Zhuo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Current Issues in Molecular Biology
Subjects:
CIPN
DRG
tumor necrosis factor α
neurite regeneration
DNA damage
mitochondrial damage
Online Access:https://www.mdpi.com/1467-3045/47/7/482
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