Systematic analysis of structural disorder in the minimal proteome of Mycoplasma pneumoniae

Systematic analysis of structural disorder in the minimal proteome of Mycoplasma pneumoniae

ABSTRACT Mycoplasma pneumoniae (Mpn, class Mollicutes) is both an important human pathogen and a model organism. We performed a proteome-wide investigation of intrinsically disordered regions (IDRs) in Mpn. Compared to other bacteria, a considerable fraction of the Mpn proteome (17%) is embedded in...

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Main Authors: Uberto Pozzoli, Diego Forni, Federica Arrigoni, Alessandra Mozzi, Rachele Cagliani, Luca De Gioia, Manuela Sironi
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
Mycoplasma pneumoniae
intrinsically disordered region
AlphaFold
structural disorder
ensemble features
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00968-25
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https://journals.asm.org/doi/10.1128/spectrum.00968-25

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