A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study
BackgroundRecent data suggest that the true incidence of atrial fibrillation (AF) after patent foramen ovale (PFO) closure has probably been underestimated, and may differ according to the type of closing device used.ObjectivesOn the basis of continuous rhythm monitoring with an implantable device,...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-04-01
|
| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1541923/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850272274347720704 |
|---|---|
| author | Stijn Lochy Alvise Del Monte Xavier Galloo Andreea Motoc Daniele Plein Kurt Hermans Frauke Gorré Julie Colas-Florial Liesbeth Rosseel Philip Muyldermans Maarten Pauwelyn Pieter-Jan Palmers François Delvoye Evelyne Wirix Jonas Podevyn Bram Roosens Philippe Unger Steven Droogmans Jean-François Argacha Sylvie De Raedt Gian Battista Chierchia Bernard Cosyns |
| author_facet | Stijn Lochy Alvise Del Monte Xavier Galloo Andreea Motoc Daniele Plein Kurt Hermans Frauke Gorré Julie Colas-Florial Liesbeth Rosseel Philip Muyldermans Maarten Pauwelyn Pieter-Jan Palmers François Delvoye Evelyne Wirix Jonas Podevyn Bram Roosens Philippe Unger Steven Droogmans Jean-François Argacha Sylvie De Raedt Gian Battista Chierchia Bernard Cosyns |
| author_sort | Stijn Lochy |
| collection | DOAJ |
| description | BackgroundRecent data suggest that the true incidence of atrial fibrillation (AF) after patent foramen ovale (PFO) closure has probably been underestimated, and may differ according to the type of closing device used.ObjectivesOn the basis of continuous rhythm monitoring with an implantable device, this study aims to assess the incidence of supraventricular arrhythmia following PFO closure with the Occlutech PFO device.MethodsThis is a multicentric analysis of consecutive PFO closure patients treated with an Occlutech device between 01/01/2019 and 20/03/2024, with an implantable loop recorder (IRL) (or a pacemaker or implantable cardioverter defibrillator) implanted for at least 3 months preceding the procedure, and with available follow-up for at least 1month post procedure. Primary endpoint was the incidence of patients with new onset supraventricular arrhythmia (AF, atrial flutter or any supraventricular tachycardia) lasting >30 s, post PFO closure.ResultsA total of 59 patients met the inclusion criteria. Patients were monitored (95% with ILR) during 284 days (IQR 241.5–374) before, and for 422 days (IQR 237–776) post PFO closure. Supraventricular arrhythmia post PFO closure was reported in 18 patients (31%), with median time-interval until arrhythmia occurrence of 16.5 days (IQR 13–21). A total of 88 supraventricular arrhythmia events (96.6% AF) were documented during follow-up. In 94.4% of patients with supraventricular arrhythmia, new-onset arrhythmia occurred in the first 45 days after PFO closure. Six patients (33.3%) with supraventricular arrhythmia post PFO closure, presented AF episodes beyond 60 days after PFO closure.ConclusionsIn this multicenter retrospective analysis of patients undergoing percutaneous PFO closure with the Occlutech PFO device, implantable continuous rhythm monitoring devices were able to diagnose new-onset supraventricular arrhythmia (97% AF) after PFO closure in 31% of patients. While 94% of new-onset supraventricular arrhythmia events occurred in the first 45 days post-procedure, one-third of patients with arrhythmia post PFO closure presented AF episodes beyond 60 days post procedure. |
| format | Article |
| id | doaj-art-e23c82e952994f1db21204a209c4b6d8 |
| institution | OA Journals |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-e23c82e952994f1db21204a209c4b6d82025-08-20T01:51:53ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-04-011210.3389/fcvm.2025.15419231541923A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR studyStijn Lochy0Alvise Del Monte1Xavier Galloo2Andreea Motoc3Daniele Plein4Kurt Hermans5Frauke Gorré6Julie Colas-Florial7Liesbeth Rosseel8Philip Muyldermans9Maarten Pauwelyn10Pieter-Jan Palmers11François Delvoye12Evelyne Wirix13Jonas Podevyn14Bram Roosens15Philippe Unger16Steven Droogmans17Jean-François Argacha18Sylvie De Raedt19Gian Battista Chierchia20Bernard Cosyns21Department of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumHeart Rhythm Management Center, Postgraduate Program in Cardiac Electrophysiology and Pacing, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Algemeen Ziekenhuis Sint-Lucas, Gent, BelgiumDepartment of Cardiology, Algemeen Ziekenhuis Sint-Lucas, Gent, BelgiumHartcentrum Aalst, AZorg, Aalst, BelgiumHartcentrum Aalst, AZorg, Aalst, BelgiumDepartment of Cardiology, Algemeen Ziekenhuis Delta, Roeselare, BelgiumDepartment of Cardiology, Algemeen Ziekenhuis Delta, Roeselare, BelgiumDepartment of Cardiology, Clinique CHC MontLégia, Luik, BelgiumDepartment of Neurology, Clinique CHC MontLégia, Luik, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), NEUR Research Group, Vrije Universiteit Brussel (VUB), Brussels, BelgiumHeart Rhythm Management Center, Postgraduate Program in Cardiac Electrophysiology and Pacing, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumDepartment of Cardiology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BelgiumBackgroundRecent data suggest that the true incidence of atrial fibrillation (AF) after patent foramen ovale (PFO) closure has probably been underestimated, and may differ according to the type of closing device used.ObjectivesOn the basis of continuous rhythm monitoring with an implantable device, this study aims to assess the incidence of supraventricular arrhythmia following PFO closure with the Occlutech PFO device.MethodsThis is a multicentric analysis of consecutive PFO closure patients treated with an Occlutech device between 01/01/2019 and 20/03/2024, with an implantable loop recorder (IRL) (or a pacemaker or implantable cardioverter defibrillator) implanted for at least 3 months preceding the procedure, and with available follow-up for at least 1month post procedure. Primary endpoint was the incidence of patients with new onset supraventricular arrhythmia (AF, atrial flutter or any supraventricular tachycardia) lasting >30 s, post PFO closure.ResultsA total of 59 patients met the inclusion criteria. Patients were monitored (95% with ILR) during 284 days (IQR 241.5–374) before, and for 422 days (IQR 237–776) post PFO closure. Supraventricular arrhythmia post PFO closure was reported in 18 patients (31%), with median time-interval until arrhythmia occurrence of 16.5 days (IQR 13–21). A total of 88 supraventricular arrhythmia events (96.6% AF) were documented during follow-up. In 94.4% of patients with supraventricular arrhythmia, new-onset arrhythmia occurred in the first 45 days after PFO closure. Six patients (33.3%) with supraventricular arrhythmia post PFO closure, presented AF episodes beyond 60 days after PFO closure.ConclusionsIn this multicenter retrospective analysis of patients undergoing percutaneous PFO closure with the Occlutech PFO device, implantable continuous rhythm monitoring devices were able to diagnose new-onset supraventricular arrhythmia (97% AF) after PFO closure in 31% of patients. While 94% of new-onset supraventricular arrhythmia events occurred in the first 45 days post-procedure, one-third of patients with arrhythmia post PFO closure presented AF episodes beyond 60 days post procedure.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1541923/fullPFO (patent foramen ovale)atrial fibrillationstructural cardiologyocclutech PFO deviceimplantable loop recorder (ILR) |
| spellingShingle | Stijn Lochy Alvise Del Monte Xavier Galloo Andreea Motoc Daniele Plein Kurt Hermans Frauke Gorré Julie Colas-Florial Liesbeth Rosseel Philip Muyldermans Maarten Pauwelyn Pieter-Jan Palmers François Delvoye Evelyne Wirix Jonas Podevyn Bram Roosens Philippe Unger Steven Droogmans Jean-François Argacha Sylvie De Raedt Gian Battista Chierchia Bernard Cosyns A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study Frontiers in Cardiovascular Medicine PFO (patent foramen ovale) atrial fibrillation structural cardiology occlutech PFO device implantable loop recorder (ILR) |
| title | A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study |
| title_full | A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study |
| title_fullStr | A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study |
| title_full_unstemmed | A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study |
| title_short | A multicenter analysis of implantable monitoring device-based diagnosis of supraventricular arrhythmia post patent foramen ovale closure: the OCCL-ILR study |
| title_sort | multicenter analysis of implantable monitoring device based diagnosis of supraventricular arrhythmia post patent foramen ovale closure the occl ilr study |
| topic | PFO (patent foramen ovale) atrial fibrillation structural cardiology occlutech PFO device implantable loop recorder (ILR) |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1541923/full |
| work_keys_str_mv | AT stijnlochy amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT alvisedelmonte amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT xaviergalloo amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT andreeamotoc amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT danieleplein amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT kurthermans amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT fraukegorre amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT juliecolasflorial amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT liesbethrosseel amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT philipmuyldermans amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT maartenpauwelyn amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT pieterjanpalmers amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT francoisdelvoye amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT evelynewirix amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT jonaspodevyn amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT bramroosens amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT philippeunger amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT stevendroogmans amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT jeanfrancoisargacha amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT sylviederaedt amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT gianbattistachierchia amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT bernardcosyns amulticenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT stijnlochy multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT alvisedelmonte multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT xaviergalloo multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT andreeamotoc multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT danieleplein multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT kurthermans multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT fraukegorre multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT juliecolasflorial multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT liesbethrosseel multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT philipmuyldermans multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT maartenpauwelyn multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT pieterjanpalmers multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT francoisdelvoye multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT evelynewirix multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT jonaspodevyn multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT bramroosens multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT philippeunger multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT stevendroogmans multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT jeanfrancoisargacha multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT sylviederaedt multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT gianbattistachierchia multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy AT bernardcosyns multicenteranalysisofimplantablemonitoringdevicebaseddiagnosisofsupraventriculararrhythmiapostpatentforamenovaleclosuretheocclilrstudy |