Simultaneous single-sample determination of NMNAT isozyme activities in mouse tissues.

A novel assay procedure has been developed to allow simultaneous activity discrimination in crude tissue extracts of the three known mammalian nicotinamide mononucleotide adenylyltransferase (NMNAT, EC 2.7.7.1) isozymes. These enzymes catalyse the same key reaction for NAD biosynthesis in different...

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Bibliographic Details
Main Authors: Giuseppe Orsomando, Lucia Cialabrini, Adolfo Amici, Francesca Mazzola, Silverio Ruggieri, Laura Conforti, Lucie Janeckova, Michael P Coleman, Giulio Magni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0053271&type=printable
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