Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil
ABSTRACT: Leishmaniasis is a parasitic disease with a worldwide distribution, transmitted to animals and humans through the blood meal of sand flies, caused by protozoa of the genus Leishmania. This report aims to describe the clinical, pathological, and molecular findings of mucocutaneous leishmani...
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Colégio Brasileiro de Patologia Animal (CBPA)
2025-08-01
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| Series: | Pesquisa Veterinária Brasileira |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2025000101101&lng=en&tlng=en |
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| author | Michelli L. de Souza Fagner D. Fernandes Gabriela Hartmann Guilherme R. Cassanego Rafael A. Fighera Fernanda S.F. Vogel Luís Antonio Sangioni |
| author_facet | Michelli L. de Souza Fagner D. Fernandes Gabriela Hartmann Guilherme R. Cassanego Rafael A. Fighera Fernanda S.F. Vogel Luís Antonio Sangioni |
| author_sort | Michelli L. de Souza |
| collection | DOAJ |
| description | ABSTRACT: Leishmaniasis is a parasitic disease with a worldwide distribution, transmitted to animals and humans through the blood meal of sand flies, caused by protozoa of the genus Leishmania. This report aims to describe the clinical, pathological, and molecular findings of mucocutaneous leishmaniasis caused by Leishmania enriettii in a guinea pig (Cavia porcellus). The animal presented ulcerated skin lesions in the right pinna. Samples from the lesion were evaluated by cytology, revealing the presence of amastigote forms of Leishmania spp. Histopathology showed a dermal inflammatory infiltrate consisting of macrophages, multinucleated giant cells, lymphocytes, plasma cells, and heterophils. The foam cells contained parasitophorous vacuoles filled with amastigotes. Molecular characterization identified the species as L. enriettii. The diagnosis of mucocutaneous leishmaniasis was based on morphological findings (macroscopic and microscopic) associated with molecular biology tests that allowed defining the etiological agent of the disease. |
| format | Article |
| id | doaj-art-e231f824672e42a7bead9f0937e59fed |
| institution | Kabale University |
| issn | 1678-5150 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Colégio Brasileiro de Patologia Animal (CBPA) |
| record_format | Article |
| series | Pesquisa Veterinária Brasileira |
| spelling | doaj-art-e231f824672e42a7bead9f0937e59fed2025-08-20T03:44:10ZengColégio Brasileiro de Patologia Animal (CBPA)Pesquisa Veterinária Brasileira1678-51502025-08-014510.1590/1678-5150-pvb-7576Leishmania enriettii in guinea pig (Cavia porcellus) in southern BrazilMichelli L. de Souzahttps://orcid.org/0000-0002-0103-6123Fagner D. Fernandeshttps://orcid.org/0000-0002-2591-2327Gabriela Hartmannhttps://orcid.org/0000-0001-8740-3053Guilherme R. Cassanegohttps://orcid.org/0000-0003-2632-2465Rafael A. Figherahttps://orcid.org/0000-0003-3391-5955Fernanda S.F. Vogelhttps://orcid.org/0000-0003-1351-9912Luís Antonio Sangionihttps://orcid.org/0000-0002-2364-1084ABSTRACT: Leishmaniasis is a parasitic disease with a worldwide distribution, transmitted to animals and humans through the blood meal of sand flies, caused by protozoa of the genus Leishmania. This report aims to describe the clinical, pathological, and molecular findings of mucocutaneous leishmaniasis caused by Leishmania enriettii in a guinea pig (Cavia porcellus). The animal presented ulcerated skin lesions in the right pinna. Samples from the lesion were evaluated by cytology, revealing the presence of amastigote forms of Leishmania spp. Histopathology showed a dermal inflammatory infiltrate consisting of macrophages, multinucleated giant cells, lymphocytes, plasma cells, and heterophils. The foam cells contained parasitophorous vacuoles filled with amastigotes. Molecular characterization identified the species as L. enriettii. The diagnosis of mucocutaneous leishmaniasis was based on morphological findings (macroscopic and microscopic) associated with molecular biology tests that allowed defining the etiological agent of the disease.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2025000101101&lng=en&tlng=enHistopathologyleishmaniasisrodentLeishmania enriettiiprotozoan |
| spellingShingle | Michelli L. de Souza Fagner D. Fernandes Gabriela Hartmann Guilherme R. Cassanego Rafael A. Fighera Fernanda S.F. Vogel Luís Antonio Sangioni Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil Pesquisa Veterinária Brasileira Histopathology leishmaniasis rodent Leishmania enriettii protozoan |
| title | Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil |
| title_full | Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil |
| title_fullStr | Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil |
| title_full_unstemmed | Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil |
| title_short | Leishmania enriettii in guinea pig (Cavia porcellus) in southern Brazil |
| title_sort | leishmania enriettii in guinea pig cavia porcellus in southern brazil |
| topic | Histopathology leishmaniasis rodent Leishmania enriettii protozoan |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2025000101101&lng=en&tlng=en |
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