GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

Diabetes mellitus (DM), a metabolic disorder syndrome characterized by persistent hyperglycemia, has a complex pathogenesis. As the number of diabetic patients continues to grow globally, this disease has become a major and growing challenge in global public health. Glucagon-like peptide-1 receptor...

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Bibliographic Details
Main Authors: Shujun Li, Nanqu Huang, Mei Wang, Wendi Huang, Yong Luo, Juan Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
glucagon-like peptide-1 receptor
diabetes mellitus
β-cell
insulin secretion
blood glucose
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1610512/full
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