A systematic review of the major risk factors for type two diabetes among Aboriginal Australians

Abstract Background To investigate the sociodemographic, anthropometric, biochemical, lifestyle and cardiometabolic risk factors associated with type 2 diabetes (T2D) among First Nations Australians. Methods A systematic review of prospective cohorts and cross-sectional studies was conducted. Electr...

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Main Authors: Utpal K. Mondal, Kedir Y. Ahmed, Subash Thapa, Bernd Kalinna, Sok Cheon Pak, Anayochukwu E. Anyasodor, Shakeel Mahmood, Muhammad J. A. Shiddiky, Allen G. Ross
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Language:English
Published: BMC 2024-11-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-024-20637-z
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author Utpal K. Mondal
Kedir Y. Ahmed
Subash Thapa
Bernd Kalinna
Sok Cheon Pak
Anayochukwu E. Anyasodor
Shakeel Mahmood
Muhammad J. A. Shiddiky
Allen G. Ross
author_facet Utpal K. Mondal
Kedir Y. Ahmed
Subash Thapa
Bernd Kalinna
Sok Cheon Pak
Anayochukwu E. Anyasodor
Shakeel Mahmood
Muhammad J. A. Shiddiky
Allen G. Ross
author_sort Utpal K. Mondal
collection DOAJ
description Abstract Background To investigate the sociodemographic, anthropometric, biochemical, lifestyle and cardiometabolic risk factors associated with type 2 diabetes (T2D) among First Nations Australians. Methods A systematic review of prospective cohorts and cross-sectional studies was conducted. Electronic data sources (MEDLINE/PubMed, Embase, CINHAL, and PsycINFO) were searched for peer-reviewed articles until August 2023. We reviewed observational and interventional studies on T2D that reported sociodemographic, anthropometric, lifestyle, and biochemical risk factors for Australian First Nations people. Narrative synthesis was applied without meta-analysis. We highlighted the major risk factors for T2D by reporting the most significant findings from individual studies in the results. The review followed PRISMA guidelines. Results The review included 20 eligible studies: 12 cross-sectional studies and 8 prospective cohort studies. The findings from these studies showed that First Nations people who resided in very remote areas (Modified Monash Category 7; MM7) (OR = 1.61; 95% CI: 1.03, 2.52), living adjacent to food store stocking “Western” food items (OR = 2.92; 95% CI: 1.51, 5.63), rented their home (OR = 2.07; 95% CI: 1.30, 3.30) and part-time employment (OR = 2.47; 95% CI: 1.54, 3.95) were associated with a statistically higher risk of developing T2D. First Nations people who had obesity class 1 (BMI > 30 kg/m2), central obesity (WC > 88 cm in women; >102 cm in men), and higher waist-to-hip ratio (WHR) (≥ 1.0 in men and 0.85 in women) were more likely to have T2D. First Nations people with elevated triglycerides (≥ 1.7 mmol/L) (OR = 4.9; 95% CI: 2.7, 8.8), one standard deviation (SD) increase in C-reactive protein (CRP) value (AHR = 1.23; 95% CI: 1.05, 1.45) and lower levels of vitamin D (< 53 nmol/L) (AOR = 2.15; 95% CI: 1.10, 2.18) were significantly associated with a higher risk of T2D. However, no significant association was found with either daily smoking or daily alcohol. Conclusion To address the First Nations Health Gap attributed to T2D in Australia, interventions should prioritise remote areas, socioeconomic disadvantage, central obesity, elevated triglycerides, and vitamin D deficiency. This was the first comprehensive systematic review examining sociodemographic, anthropometric, biochemical, lifestyle, and cardiometabolic risk factors associated with T2D among First Nations Australians.
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spelling doaj-art-e22afcd7e1374a59910ad7afdc07ee552024-11-24T12:46:49ZengBMCBMC Public Health1471-24582024-11-0124111510.1186/s12889-024-20637-zA systematic review of the major risk factors for type two diabetes among Aboriginal AustraliansUtpal K. Mondal0Kedir Y. Ahmed1Subash Thapa2Bernd Kalinna3Sok Cheon Pak4Anayochukwu E. Anyasodor5Shakeel Mahmood6Muhammad J. A. Shiddiky7Allen G. Ross8Rural Health Research Institute, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversitySchool of Dentistry and Medical Sciences, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversityRural Health Research Institute, Charles Sturt UniversityAbstract Background To investigate the sociodemographic, anthropometric, biochemical, lifestyle and cardiometabolic risk factors associated with type 2 diabetes (T2D) among First Nations Australians. Methods A systematic review of prospective cohorts and cross-sectional studies was conducted. Electronic data sources (MEDLINE/PubMed, Embase, CINHAL, and PsycINFO) were searched for peer-reviewed articles until August 2023. We reviewed observational and interventional studies on T2D that reported sociodemographic, anthropometric, lifestyle, and biochemical risk factors for Australian First Nations people. Narrative synthesis was applied without meta-analysis. We highlighted the major risk factors for T2D by reporting the most significant findings from individual studies in the results. The review followed PRISMA guidelines. Results The review included 20 eligible studies: 12 cross-sectional studies and 8 prospective cohort studies. The findings from these studies showed that First Nations people who resided in very remote areas (Modified Monash Category 7; MM7) (OR = 1.61; 95% CI: 1.03, 2.52), living adjacent to food store stocking “Western” food items (OR = 2.92; 95% CI: 1.51, 5.63), rented their home (OR = 2.07; 95% CI: 1.30, 3.30) and part-time employment (OR = 2.47; 95% CI: 1.54, 3.95) were associated with a statistically higher risk of developing T2D. First Nations people who had obesity class 1 (BMI > 30 kg/m2), central obesity (WC > 88 cm in women; >102 cm in men), and higher waist-to-hip ratio (WHR) (≥ 1.0 in men and 0.85 in women) were more likely to have T2D. First Nations people with elevated triglycerides (≥ 1.7 mmol/L) (OR = 4.9; 95% CI: 2.7, 8.8), one standard deviation (SD) increase in C-reactive protein (CRP) value (AHR = 1.23; 95% CI: 1.05, 1.45) and lower levels of vitamin D (< 53 nmol/L) (AOR = 2.15; 95% CI: 1.10, 2.18) were significantly associated with a higher risk of T2D. However, no significant association was found with either daily smoking or daily alcohol. Conclusion To address the First Nations Health Gap attributed to T2D in Australia, interventions should prioritise remote areas, socioeconomic disadvantage, central obesity, elevated triglycerides, and vitamin D deficiency. This was the first comprehensive systematic review examining sociodemographic, anthropometric, biochemical, lifestyle, and cardiometabolic risk factors associated with T2D among First Nations Australians.https://doi.org/10.1186/s12889-024-20637-zDiabetes mellitusRisk factorsAboriginal and torres strait islandersFirst nationsAustralia
spellingShingle Utpal K. Mondal
Kedir Y. Ahmed
Subash Thapa
Bernd Kalinna
Sok Cheon Pak
Anayochukwu E. Anyasodor
Shakeel Mahmood
Muhammad J. A. Shiddiky
Allen G. Ross
A systematic review of the major risk factors for type two diabetes among Aboriginal Australians
BMC Public Health
Diabetes mellitus
Risk factors
Aboriginal and torres strait islanders
First nations
Australia
title A systematic review of the major risk factors for type two diabetes among Aboriginal Australians
title_full A systematic review of the major risk factors for type two diabetes among Aboriginal Australians
title_fullStr A systematic review of the major risk factors for type two diabetes among Aboriginal Australians
title_full_unstemmed A systematic review of the major risk factors for type two diabetes among Aboriginal Australians
title_short A systematic review of the major risk factors for type two diabetes among Aboriginal Australians
title_sort systematic review of the major risk factors for type two diabetes among aboriginal australians
topic Diabetes mellitus
Risk factors
Aboriginal and torres strait islanders
First nations
Australia
url https://doi.org/10.1186/s12889-024-20637-z
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