Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction

Aim. To create a calculator for the annual personalised risk assessment of adverse cardiovascular events in patients after acute ST-segment elevation myocardial infarction (STEMI).Materials and Methods. Here we performed a prospective data analysis of 1,000 patients diagnosed with STEMI during 2017...

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Main Authors: V. B. Barbarich, N. G. Lozhkina, A. A. Tolmacheva, M. H. Hasanova, E. A. Stafeeva, I. Mukaramov, O. M. Parhomenko, A. D. Kuimov, Ju. E. Voskobojnikov
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2020-06-01
Series:Фундаментальная и клиническая медицина
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Online Access:https://fcm.kemsmu.ru/jour/article/view/262
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author V. B. Barbarich
N. G. Lozhkina
A. A. Tolmacheva
M. H. Hasanova
E. A. Stafeeva
I. Mukaramov
O. M. Parhomenko
A. D. Kuimov
Ju. E. Voskobojnikov
author_facet V. B. Barbarich
N. G. Lozhkina
A. A. Tolmacheva
M. H. Hasanova
E. A. Stafeeva
I. Mukaramov
O. M. Parhomenko
A. D. Kuimov
Ju. E. Voskobojnikov
author_sort V. B. Barbarich
collection DOAJ
description Aim. To create a calculator for the annual personalised risk assessment of adverse cardiovascular events in patients after acute ST-segment elevation myocardial infarction (STEMI).Materials and Methods. Here we performed a prospective data analysis of 1,000 patients diagnosed with STEMI during 2017 and 2018 and admitted to Regional Vascular Center. For evaluating the risk of adverse cardiovascular events after STEMI, we applied the GRACE scale. After 1 year of follow-up, the predicted outcomes were compared with the actual outcomes. We then created a personalised calculator of unfavorable outcome by using logistic regression.Results. The calculator included six indicators that significantly correlated with outcomes and poorly correlated with each other: left ventricular ejection fraction (LVEF) < 40%, anterior STEMI, tachycardia upon admission, fasting blood glucose, high-sensitive C-reactive protein (CRP), and patient age.Conclusion. We found a high reliability of our calculator for the annual personalised prognosis of adverse outcome in patients after STEMI.
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institution Kabale University
issn 2500-0764
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language Russian
publishDate 2020-06-01
publisher Kemerovo State Medical University
record_format Article
series Фундаментальная и клиническая медицина
spelling doaj-art-e22183003f464e989373526e98664e5a2025-08-20T03:57:40ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412020-06-0152485910.23946/2500-0764-2020-5-2-48-59201Annual personalised calculator for prognostication after ST-segment elevation myocardial infarctionV. B. Barbarich0N. G. Lozhkina1A. A. Tolmacheva2M. H. Hasanova3E. A. Stafeeva4I. Mukaramov5O. M. Parhomenko6A. D. Kuimov7Ju. E. Voskobojnikov8Novosibirsk State Medical University; City Clinical Hospital # 1Novosibirsk State Medical UniversityNovosibirsk State Medical UniversityNovosibirsk State Medical UniversityNovosibirsk State Medical UniversityNovosibirsk State Medical UniversityCity Clinical Hospital # 1Novosibirsk State Medical UniversityNovosibirsk State University of Architecture and Civil EngineeringAim. To create a calculator for the annual personalised risk assessment of adverse cardiovascular events in patients after acute ST-segment elevation myocardial infarction (STEMI).Materials and Methods. Here we performed a prospective data analysis of 1,000 patients diagnosed with STEMI during 2017 and 2018 and admitted to Regional Vascular Center. For evaluating the risk of adverse cardiovascular events after STEMI, we applied the GRACE scale. After 1 year of follow-up, the predicted outcomes were compared with the actual outcomes. We then created a personalised calculator of unfavorable outcome by using logistic regression.Results. The calculator included six indicators that significantly correlated with outcomes and poorly correlated with each other: left ventricular ejection fraction (LVEF) < 40%, anterior STEMI, tachycardia upon admission, fasting blood glucose, high-sensitive C-reactive protein (CRP), and patient age.Conclusion. We found a high reliability of our calculator for the annual personalised prognosis of adverse outcome in patients after STEMI.https://fcm.kemsmu.ru/jour/article/view/262myocardial infarctionpersonalized medicineacute myocardial infarction with st-segment elevation (stemi)long-term prognosis
spellingShingle V. B. Barbarich
N. G. Lozhkina
A. A. Tolmacheva
M. H. Hasanova
E. A. Stafeeva
I. Mukaramov
O. M. Parhomenko
A. D. Kuimov
Ju. E. Voskobojnikov
Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction
Фундаментальная и клиническая медицина
myocardial infarction
personalized medicine
acute myocardial infarction with st-segment elevation (stemi)
long-term prognosis
title Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction
title_full Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction
title_fullStr Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction
title_full_unstemmed Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction
title_short Annual personalised calculator for prognostication after ST-segment elevation myocardial infarction
title_sort annual personalised calculator for prognostication after st segment elevation myocardial infarction
topic myocardial infarction
personalized medicine
acute myocardial infarction with st-segment elevation (stemi)
long-term prognosis
url https://fcm.kemsmu.ru/jour/article/view/262
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