HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER
The hereditary breast cancer (HBC) occurs in 5–10 % of all cases of breast cancer. The mutations in the genes of high penetrance – BRCA1, BRCA2 is mainly the reason HBC. In the study presented the features of HBC (age of onset of the disease, cancer family history, primary tumor process multiple cha...
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| Format: | Article |
| Language: | Russian |
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Russian Academy of Sciences, Tomsk National Research Medical Center
2016-02-01
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| Series: | Сибирский онкологический журнал |
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| Online Access: | https://www.siboncoj.ru/jour/article/view/260 |
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| _version_ | 1850030544843177984 |
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| author | Е. М. Bit-Sava |
| author_facet | Е. М. Bit-Sava |
| author_sort | Е. М. Bit-Sava |
| collection | DOAJ |
| description | The hereditary breast cancer (HBC) occurs in 5–10 % of all cases of breast cancer. The mutations in the genes of high penetrance – BRCA1, BRCA2 is mainly the reason HBC. In the study presented the features of HBC (age of onset of the disease, cancer family history, primary tumor process multiple character). Depending on the presence of mutations BRCA1 5382insC, BLM, CHEK2 carried out a comparative analysis of the occurrence of hereditary characteristics in breast cancer patients. |
| format | Article |
| id | doaj-art-e2211e4443ba4672b55fac55beca6bab |
| institution | DOAJ |
| issn | 1814-4861 2312-3168 |
| language | Russian |
| publishDate | 2016-02-01 |
| publisher | Russian Academy of Sciences, Tomsk National Research Medical Center |
| record_format | Article |
| series | Сибирский онкологический журнал |
| spelling | doaj-art-e2211e4443ba4672b55fac55beca6bab2025-08-20T02:59:11ZrusRussian Academy of Sciences, Tomsk National Research Medical CenterСибирский онкологический журнал1814-48612312-31682016-02-01061518260HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCERЕ. М. Bit-Sava0St-Petersburg State Pediatric Medical Academy St-Petersburg I.P. Pavlov State Medical UniversityThe hereditary breast cancer (HBC) occurs in 5–10 % of all cases of breast cancer. The mutations in the genes of high penetrance – BRCA1, BRCA2 is mainly the reason HBC. In the study presented the features of HBC (age of onset of the disease, cancer family history, primary tumor process multiple character). Depending on the presence of mutations BRCA1 5382insC, BLM, CHEK2 carried out a comparative analysis of the occurrence of hereditary characteristics in breast cancer patients.https://www.siboncoj.ru/jour/article/view/260hereditary breast cancerbrca1 5382inscblmchek2 |
| spellingShingle | Е. М. Bit-Sava HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER Сибирский онкологический журнал hereditary breast cancer brca1 5382insc blm chek2 |
| title | HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER |
| title_full | HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER |
| title_fullStr | HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER |
| title_full_unstemmed | HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER |
| title_short | HEREDITARY CHARACTERISTICS BRCA1 5382INSC/СHEK2/BLM-ASSOCIATED BREAST CANCER |
| title_sort | hereditary characteristics brca1 5382insc сhek2 blm associated breast cancer |
| topic | hereditary breast cancer brca1 5382insc blm chek2 |
| url | https://www.siboncoj.ru/jour/article/view/260 |
| work_keys_str_mv | AT embitsava hereditarycharacteristicsbrca15382inscshek2blmassociatedbreastcancer |