Structural characterization of HDAC2-MTA1 complex

Structural characterization of HDAC2-MTA1 complex

Histone deacetylases are recruited to specific transcriptional repression complexes through interactions with corepressor proteins. This recruitment leads to chromatin condensation and transcriptional silencing. In this study, we modeled the complex structure of HDAC2 with MTA1 and investigated the...

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Bibliographic Details
Main Authors:	Narayan Gautam, Narayan Prasad Adhikari
Format:	Article
Language:	English
Published:	Department of Physics, Mahendra Morang Adarsh Multiple Campus, Tribhuvan University 2025-05-01
Series:	Bibechana
Subjects:	HDAC2 MTA1 Molecular dynamics simulation Hydrogen bonding Hydrophobic interactions Solvent-accessible surface area
Online Access:	https://www.nepjol.info/index.php/BIBECHANA/article/view/74254
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