The Rare Instance of Uterine Adenocarcinoma Metastasizing to the Skull Base, Manifesting as Blindness and Ptosis

Metastasis to the skull base is a rare but serious complication of various malignancies. This case report  discusses a 50-year-old woman with a history of advanced endometrialadenocarcinoma who presented with progressive headache, left-eye blindness, and ptosis. Imaging revealed a mass along the le...

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Bibliographic Details
Main Authors: Zahra Sanayepasand, Shirin Irani, Mohammadreza Firouzifar, Seyede Misha Seyednia, Farrokh Heidari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-11-01
Series:Case Reports in Clinical Practice
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Online Access:https://crcp.tums.ac.ir/index.php/crcp/article/view/985
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Summary:Metastasis to the skull base is a rare but serious complication of various malignancies. This case report  discusses a 50-year-old woman with a history of advanced endometrialadenocarcinoma who presented with progressive headache, left-eye blindness, and ptosis. Imaging revealed a mass along the left optic nerve, raising suspicions of mucormycosis, but biopsy confirmed metastatic endometrial adenocarcinoma. Despite undergoing skull base radiotherapy, the patient’s vision did not improve. This case underscores the importance of considering metastatic endometrial adenocarcinoma in differential diagnoses for skull base lesions, particularly when other conditions are ruled out. Accurate diagnosis requires careful integration of clinical, radiological, and histopathological data.
ISSN:2538-2683
2538-2691