A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate

A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate

The formation of the mammalian brain requires regionalization and morphogenesis of the cranial neural plate, which transforms from an epithelial sheet into a closed tube that provides the structural foundation for neural patterning and circuit formation. Sonic hedgehog (SHH) signaling is important f...

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Bibliographic Details
Main Authors: Eric R Brooks, Andrew R Moorman, Bhaswati Bhattacharya, Ian S Prudhomme, Max Land, Heather L Alcorn, Roshan Sharma, Dana Pe'er, Jennifer A Zallen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-04-01
Series:eLife
Subjects:
single-cell RNA sequencing
mouse embryo
neural plate
brain development
patterning
neural tube closure
Online Access:https://elifesciences.org/articles/102819
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