Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case

The case we report shows rapid progression and a very poor prognosis only for a month that differs from the clinical course reported in the literature. An 83-year-old man was referred to our hospital for macroscopic hematuria. Computed tomography (CT) revealed a large bladder tumor measuring 4 cm × ...

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Main Authors: Toru Yamada, Shingo Nagai, Yusuke Kanimoto
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2011/532081
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author Toru Yamada
Shingo Nagai
Yusuke Kanimoto
author_facet Toru Yamada
Shingo Nagai
Yusuke Kanimoto
author_sort Toru Yamada
collection DOAJ
description The case we report shows rapid progression and a very poor prognosis only for a month that differs from the clinical course reported in the literature. An 83-year-old man was referred to our hospital for macroscopic hematuria. Computed tomography (CT) revealed a large bladder tumor measuring 4 cm × 3 cm and magnetic resonance imaging revealed extravesical invasion and pelvic wall invasion of the tumors. Chest CT and bone scintigraphy revealed no evidence of distant visceral metastases, and a clinical diagnosis of T4N0M0 was made. Transurethral resection of the bladder tumor (TUR-BT) was performed for histopathological diagnosis 18 days after admission, and no further adjuvant treatment was given. At 15 days after TUR-BT, the patient's clinical status worsened with symptoms of exertional dyspnea. CT showed multiple metastatic lesions in the lung, liver, and retroperitoneal lymphadenopathy. The patient died 2 days later and underwent autopsy. A final histopathological diagnosis of leiomyosarcoma was made based on immunohistochemical staining.
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spelling doaj-art-e20e1d6b56db42d5aa03c6b8fc6fc5662025-08-20T02:21:38ZengWileyCase Reports in Urology2090-696X2090-69782011-01-01201110.1155/2011/532081532081Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a CaseToru Yamada0Shingo Nagai1Yusuke Kanimoto2Department of Urology, Kakegawa Municipal General Hospital, Shizuoka-ken 436-8502, JapanDepartment of Urology, Kakegawa Municipal General Hospital, Shizuoka-ken 436-8502, JapanDepartment of Urology, Kakegawa Municipal General Hospital, Shizuoka-ken 436-8502, JapanThe case we report shows rapid progression and a very poor prognosis only for a month that differs from the clinical course reported in the literature. An 83-year-old man was referred to our hospital for macroscopic hematuria. Computed tomography (CT) revealed a large bladder tumor measuring 4 cm × 3 cm and magnetic resonance imaging revealed extravesical invasion and pelvic wall invasion of the tumors. Chest CT and bone scintigraphy revealed no evidence of distant visceral metastases, and a clinical diagnosis of T4N0M0 was made. Transurethral resection of the bladder tumor (TUR-BT) was performed for histopathological diagnosis 18 days after admission, and no further adjuvant treatment was given. At 15 days after TUR-BT, the patient's clinical status worsened with symptoms of exertional dyspnea. CT showed multiple metastatic lesions in the lung, liver, and retroperitoneal lymphadenopathy. The patient died 2 days later and underwent autopsy. A final histopathological diagnosis of leiomyosarcoma was made based on immunohistochemical staining.http://dx.doi.org/10.1155/2011/532081
spellingShingle Toru Yamada
Shingo Nagai
Yusuke Kanimoto
Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case
Case Reports in Urology
title Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case
title_full Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case
title_fullStr Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case
title_full_unstemmed Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case
title_short Rapid Progression of a Urinary Bladder Leiomyosarcoma: Report of a Case
title_sort rapid progression of a urinary bladder leiomyosarcoma report of a case
url http://dx.doi.org/10.1155/2011/532081
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