Antimicrobial and ADME properties of methoxylated, methylated and nitrated 2-hydroxynaphthalene-1 carboxanilides

Antimicrobial and ADME properties of methoxylated, methylated and nitrated 2-hydroxynaphthalene-1 carboxanilides

Background and purpose: Many new compounds are being prepared to overcome the problem of increasing microbial resistance and the increasing number of infections. Experimental approach: This study includes a series of twenty-seven mono-, di- and trisubstituted 2-hydroxynaphthalene-1-carboxanilides d...

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Bibliographic Details
Main Authors: Lucia Vrablova, Tomas Gonec, Tereza Kauerova, Michal Oravec, Izabela Jendrzejewska, Peter Kollar, Alois Cizek, Josef Jampilek
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2025-02-01
Series:ADMET and DMPK
Subjects:
lipophilicity
antibacterial activity
antimycobacterial activity
cytotoxicity
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/2642
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