Mitochondrial ultrastructural pathology in diabetic cardiomyopathy: integrated analysis via scanning electron microscopy and 3D visualization imaging

Mitochondrial ultrastructural pathology in diabetic cardiomyopathy: integrated analysis via scanning electron microscopy and 3D visualization imaging

Abstract Background Mitochondrial dysfunction plays a pivotal role in the onset and progression of diabetic cardiomyopathy (DCM). It is hypothesized that ultrastructural mitochondrial abnormalities, molecular dynamics imbalance, and bioenergetic impairments collectively contribute significantly to c...

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Bibliographic Details
Main Authors: Bo Wang, Linghao Dai, Haowei Liang, Jiayu He, Jiayi Zhou, Yang Guan, Hui Wang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cardiovascular Diabetology
Subjects:
Diabetic cardiomyopathy
Mitochondria
Ultrastructure
Energy metabolism
Scanning electron microscopy
3D visualization imaging
Online Access:https://doi.org/10.1186/s12933-025-02884-5
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