Impact of gonadotropin genetic profile and ovarian reserve on controlled ovarian stimulation: data from prospective cohort of the GENOCS trial

Impact of gonadotropin genetic profile and ovarian reserve on controlled ovarian stimulation: data from prospective cohort of the GENOCS trial

IntroductionSeveral studies indicate that a specific genotype profile could influence ovarian sensitivity to exogenous gonadotropin. However, most of the previous studies were observational and retrospective and thereby more prone to bias. The aim of this study was to evaluate the impact of gonadotr...

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Main Authors: Alessandro Conforti, Daniele Santi, Adolfo Allegra, Mario Mignini Renzini, Angelo Marino, Claudio Brigante, Roberta Iemmello, Valeria Stella Vanni, Agnese Rebecchi, Laura Privitera, Samantha Sperduti, Livio Casarini, Ilma Floriana Carbone, Manuela Simoni, Carlo Alviggi, Enrico Papaleo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Endocrinology
Subjects:
polymorphisms
pharmacogenomic
ovarian stimulation
IVF/ICSI
ART
genetic variants
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1601803/full
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