Brugia Malayi: Depletion of Glutathione by Buthionine Sulfoximine
Glutathione is an intracellular reducing agent. It is synthesized by a two-step reaction catalyzed by ?-glutamylcysteine synthetase (?GCS) and glutathione synthetase. ?GCS, which is the rate limiting enzyme in the synthesis of glutathione, is inhibited specifically by buthionine sulfoximine (BSO). T...
Saved in:
| Main Author: | Ayman Hussein |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
An-Najah National University
2005-08-01
|
| Series: | مجلة جامعة النجاح للأبحاث العلوم الطبيعية |
| Online Access: | https://journals.najah.edu/media/journals/full_texts/brugia-malayi-depletion-glutathione-buthionine-sulfoximine.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Live Brugia malayi microfilariae inhibit transendothelial migration of neutrophils and monocytes.
by: Jan-Hendrik Schroeder, et al.
Published: (2012-01-01) -
New insights into the genetic diversity, phylogeny, and immunogenic potential of the wsp gene in Wolbachia endosymbionts in Brugia malayi and Brugia pahangi
by: Witchuta Junsiri, et al.
Published: (2025-01-01) -
Dose-Dependent Prophylactic Efficacy of Filarial Antigens Glutathione-S-Transferase and Abundant Larval Transcript-2 against Brugia malayi Challenge in Mastomys
by: Mohini Rambhau Nakhale, et al.
Published: (2024-01-01) -
Retraction: Synergistic Apoptosis of CML cells by buthionine sulfoximine and hydroxychavicol correlates with activation of AIF and GSH-ROS-JNK-ERK-iNOS pathway.
by: PLOS One Editors
Published: (2025-01-01) -
Development of an in vivo RNAi protocol to investigate gene function in the filarial nematode, Brugia malayi.
by: Chuanzhe Song, et al.
Published: (2010-12-01)