NOX proteins and ROS generation: role in invadopodia formation and cancer cell invasion

NOX proteins and ROS generation: role in invadopodia formation and cancer cell invasion

Abstract NADPH oxidases (NOX) are membrane-bound proteins involved in the localized generation of reactive oxygen species (ROS) at the cellular surface. In cancer, these highly reactive molecules primarily originate in mitochondria and via NOX, playing a crucial role in regulating fundamental cellul...

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Bibliographic Details
Main Authors: Nelson Quilaqueo-Millaqueo, David A. Brown-Brown, Jetzabel A. Vidal-Vidal, Ignacio Niechi
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Biological Research
Subjects:
NOX
ROS
Invadopodia
Cancer cell invasion
Online Access:https://doi.org/10.1186/s40659-024-00577-z
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