ERMAP attenuates DSS-induced colitis in mice by regulating macrophage and T cell functions

ERMAP attenuates DSS-induced colitis in mice by regulating macrophage and T cell functions

Abstract Background & aims Both macrophages and T cells play a critical role in inflammatory bowel disease (IBD) development. Since our previous studies have shown that a novel immune checkpoint molecule erythrocyte membrane-associated protein (ERMAP) affects macrophage polarization and negative...

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Bibliographic Details
Main Authors: Lu Xia, Yiwen Pan, Xianbin Wang, Rong Hu, Jie Gao, Wei Chen, Keke He, Dongbin Cui, Youbo Zhao, Lu Liu, Laijun Lai, Min Su
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Gastroenterology
Subjects:
ERMAP
Inflammatory bowel disease
Macrophages
T cells
Online Access:https://doi.org/10.1186/s12876-025-03840-z
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