The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients

The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients

Abstract Background Pediatric septic shock is a critical condition associated with high mortality rates, largely due to sepsis-induced immunosuppression. Granulocyte-macrophage colony-stimulating factor (GM-CSF) has been explored as a therapeutic intervention to counteract this immunosuppression. De...

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Main Authors: Zhen-Hao Yu, Gui-Xiang Tian, Yao-Dong Wang, Ting-Yan Liu, Peng Shi, Jia-Yun Ying, Wei-Ming Chen, Yu-Feng Zhou, Guo-Ping Lu, Cai-Yan Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Italian Journal of Pediatrics
Subjects:
Pediatric
Sepstic shock
Immunomodulation
Immunotherapy
GM-CSF
Online Access:https://doi.org/10.1186/s13052-025-01863-6
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