The role and mechanism of lung microbiota in coal mine dust-induced NLRP3 inflammasome upregulate and lung injury

The role and mechanism of lung microbiota in coal mine dust-induced NLRP3 inflammasome upregulate and lung injury

Abstract The exact molecular mechanisms of coal workers’ pneumoconiosis (CWP) are still unknown. The purpose of this study is to investigate how the lung microbiota may contribute to the development of CWP. The rats were divided into five groups, including the control group, CWP group, silicosis gro...

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Bibliographic Details
Main Authors: Yao Zhang, Jiaju Yan, Yuan Ren, Lifang Li, Xiaojie You, Yujia Xie, Weihong Chen, Hui Zhao, Dongming Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Coal workers’ pneumoconiosis
Lung microbiota
Nod-like receptor binding protein 3
Inflammation
Fibrosis
Online Access:https://doi.org/10.1038/s41598-025-06411-0
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https://doi.org/10.1038/s41598-025-06411-0

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