Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds
Abstract Sheep breeding in Kazakhstan is one of the main local roles in animal husbandry. This article presents the results of a study of the genetic indicators of sheep breeds in Kazakhstan, in relation to their meat and wool productivity. Genetic analysis was carried out using the ROH (runs of hom...
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Instituto Internacional de Ecologia
2025-05-01
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| Series: | Brazilian Journal of Biology |
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| author | A. Khamzina D. Smagulov K. Dossybayev J. Kantanen K. Khamzin |
| author_facet | A. Khamzina D. Smagulov K. Dossybayev J. Kantanen K. Khamzin |
| author_sort | A. Khamzina |
| collection | DOAJ |
| description | Abstract Sheep breeding in Kazakhstan is one of the main local roles in animal husbandry. This article presents the results of a study of the genetic indicators of sheep breeds in Kazakhstan, in relation to their meat and wool productivity. Genetic analysis was carried out using the ROH (runs of homozygosity) method and candidate genes for various kinds of productivity traits were identified. The lowest mean genomic inbreeding coefficient values were observed in the Kazakh fine-wool breed and the Edilbay breed (FROH = 0.039 and FROH = 0.037). The highest values of inbreeding coefficient were in the Saryarka breed (FROH = 0.043), the Akzhaiyk breed (FROH = 0.044), and the Kazakh semi-coarse breed (FROH = 0.040). Since all these breeds possess the phenotypic traits for good meat constitution, the MSTN gene on the registered ROH islands has been identified and was found in all five breeds. In addition, genes affecting meat yield, adaptive traits, reproductive systems, immune systems, average daily weight gain, percentage of carcass fat, and third lumbar fat were observed within the recorded ROH islands using the Sheep QTL database. The results from the study of five breeds of sheep presented in the article are relevant (depending on the desired productivity traits) and have practical significance since only constitutionally strong animals, without exterior flaws and with high resistance to existing environmental factors, are able to produce higher yields and provide profitability to the sheep industry. |
| format | Article |
| id | doaj-art-e1dc06efeb0b42c2bb106691c53c1f59 |
| institution | OA Journals |
| issn | 1678-4375 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Instituto Internacional de Ecologia |
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| series | Brazilian Journal of Biology |
| spelling | doaj-art-e1dc06efeb0b42c2bb106691c53c1f592025-08-20T01:56:56ZengInstituto Internacional de EcologiaBrazilian Journal of Biology1678-43752025-05-018510.1590/1519-6984.292980Assessing runs of homozygosity reveals production traits of Kazakh sheep breedsA. Khamzinahttps://orcid.org/0000-0003-2211-0377D. Smagulovhttps://orcid.org/0000-0001-8992-2244K. Dossybayevhttps://orcid.org/0000-0003-1136-833XJ. Kantanenhttps://orcid.org/0000-0001-6350-6373K. Khamzinhttps://orcid.org/0000-0002-6523-6335Abstract Sheep breeding in Kazakhstan is one of the main local roles in animal husbandry. This article presents the results of a study of the genetic indicators of sheep breeds in Kazakhstan, in relation to their meat and wool productivity. Genetic analysis was carried out using the ROH (runs of homozygosity) method and candidate genes for various kinds of productivity traits were identified. The lowest mean genomic inbreeding coefficient values were observed in the Kazakh fine-wool breed and the Edilbay breed (FROH = 0.039 and FROH = 0.037). The highest values of inbreeding coefficient were in the Saryarka breed (FROH = 0.043), the Akzhaiyk breed (FROH = 0.044), and the Kazakh semi-coarse breed (FROH = 0.040). Since all these breeds possess the phenotypic traits for good meat constitution, the MSTN gene on the registered ROH islands has been identified and was found in all five breeds. In addition, genes affecting meat yield, adaptive traits, reproductive systems, immune systems, average daily weight gain, percentage of carcass fat, and third lumbar fat were observed within the recorded ROH islands using the Sheep QTL database. The results from the study of five breeds of sheep presented in the article are relevant (depending on the desired productivity traits) and have practical significance since only constitutionally strong animals, without exterior flaws and with high resistance to existing environmental factors, are able to produce higher yields and provide profitability to the sheep industry.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842025000100203&lng=en&tlng=enkazakh sheep breedsDNAovine 50K SNPrun of homozygosityinbreeding coefficientcandidate genesproductive traits |
| spellingShingle | A. Khamzina D. Smagulov K. Dossybayev J. Kantanen K. Khamzin Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds Brazilian Journal of Biology kazakh sheep breeds DNA ovine 50K SNP run of homozygosity inbreeding coefficient candidate genes productive traits |
| title | Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds |
| title_full | Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds |
| title_fullStr | Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds |
| title_full_unstemmed | Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds |
| title_short | Assessing runs of homozygosity reveals production traits of Kazakh sheep breeds |
| title_sort | assessing runs of homozygosity reveals production traits of kazakh sheep breeds |
| topic | kazakh sheep breeds DNA ovine 50K SNP run of homozygosity inbreeding coefficient candidate genes productive traits |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842025000100203&lng=en&tlng=en |
| work_keys_str_mv | AT akhamzina assessingrunsofhomozygosityrevealsproductiontraitsofkazakhsheepbreeds AT dsmagulov assessingrunsofhomozygosityrevealsproductiontraitsofkazakhsheepbreeds AT kdossybayev assessingrunsofhomozygosityrevealsproductiontraitsofkazakhsheepbreeds AT jkantanen assessingrunsofhomozygosityrevealsproductiontraitsofkazakhsheepbreeds AT kkhamzin assessingrunsofhomozygosityrevealsproductiontraitsofkazakhsheepbreeds |