Identification of disulfidptosis in esophageal squamous cell carcinoma based on single-cell and bulk RNA-seq data to predict prognosis and treatment response

Identification of disulfidptosis in esophageal squamous cell carcinoma based on single-cell and bulk RNA-seq data to predict prognosis and treatment response

PurposeOur study aims to identify the molecular subtypes of genes associated with disulfidptosis in esophageal squamous cell carcinoma(ESCC), develop a prognostic model, and identify potential therapeutic targets.MethodsBased on the GSE53625 expression profile data, we identified molecular subtypes...

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Bibliographic Details
Main Authors: Xiaodan Zhang, Jianting Du, Xiao Lin, Shuliang Zhang, Taidui Zeng, Maohui Chen, Guanglei Huang, Chun Chen, Bin Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
disulfidptosis
esophageal squamous cell carcinoma
prognostic analysis
single-cell transcriptomic analysis
therapeutic strategy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567793/full
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